6ixe

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'''Unreleased structure'''
 
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The entry 6ixe is ON HOLD until Paper Publication
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==Crystal structure of SeMet apo SH3BP5 (I41)==
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<StructureSection load='6ixe' size='340' side='right'caption='[[6ixe]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6ixe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IXE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IXE FirstGlance]. <br>
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Description:
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ixe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ixe OCA], [http://pdbe.org/6ixe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ixe RCSB], [http://www.ebi.ac.uk/pdbsum/6ixe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ixe ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/3BP5_HUMAN 3BP5_HUMAN]] Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.<ref>PMID:10339589</ref> <ref>PMID:9571151</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Fukai, S]]
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[[Category: Goto-Ito, S]]
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[[Category: Sato, Y]]
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[[Category: Yamagata, A]]
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[[Category: Gef]]
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[[Category: Rab11]]
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[[Category: Sh3bp5]]
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[[Category: Signaling protein]]

Revision as of 07:59, 20 March 2019

Crystal structure of SeMet apo SH3BP5 (I41)

PDB ID 6ixe

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