5zbt
From Proteopedia
(Difference between revisions)
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==Structure of legume lectin-like domain from Entamoeba histolytica== | ==Structure of legume lectin-like domain from Entamoeba histolytica== | ||
| - | <StructureSection load='5zbt' size='340' side='right' caption='[[5zbt]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='5zbt' size='340' side='right'caption='[[5zbt]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5zbt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZBT FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5zbt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Entamoeba_histolytica_hm-1:imss-a Entamoeba histolytica hm-1:imss-a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZBT FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zbt OCA], [http://pdbe.org/5zbt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zbt RCSB], [http://www.ebi.ac.uk/pdbsum/5zbt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zbt ProSAT]</span></td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EHI7A_000050 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=885318 Entamoeba histolytica HM-1:IMSS-A])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zbt OCA], [http://pdbe.org/5zbt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zbt RCSB], [http://www.ebi.ac.uk/pdbsum/5zbt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zbt ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | ERGIC-53-like proteins are type I membrane proteins that belong to the class of intracellular cargo receptors and are known to be indispensable for the intracellular transport of glycoproteins. They are implicated in transporting glycoproteins between the endoplasmic reticulum and the Golgi body. The crystal structure of the legume lectin-like domain of an ERGIC-53-like protein from Entamoeba histolytica has been determined at 2.4 A resolution. Although the overall structure of the domain resembles those of its mammalian and yeast orthologs (ERGIC-53 and Emp46, respectively), there are significant changes in the carbohydrate-binding site. A sequence-based search revealed the presence of several homologs of ERGIC-53 in different species of Entamoeba. This is the first report of the structural characterization of a member of this class of proteins from a protozoan and serves to further knowledge and understanding regarding the species-specific differences. | ||
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| + | Crystal structure of the legume lectin-like domain of an ERGIC-53-like protein from Entamoeba histolytica.,Khan F, Suguna K Acta Crystallogr F Struct Biol Commun. 2019 Mar 1;75(Pt 3):197-204. doi:, 10.1107/S2053230X19000499. Epub 2019 Feb 21. PMID:30839295<ref>PMID:30839295</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 5zbt" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Entamoeba histolytica hm-1:imss-a]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Khan, F]] | [[Category: Khan, F]] | ||
[[Category: Suguna, K]] | [[Category: Suguna, K]] | ||
[[Category: Ergic-like]] | [[Category: Ergic-like]] | ||
[[Category: Unknown function]] | [[Category: Unknown function]] | ||
Revision as of 08:18, 20 March 2019
Structure of legume lectin-like domain from Entamoeba histolytica
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