6mzx
From Proteopedia
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<StructureSection load='6mzx' size='340' side='right'caption='[[6mzx]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='6mzx' size='340' side='right'caption='[[6mzx]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6mzx]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MZX FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6mzx]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Halo1 Halo1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MZX FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6mzy|6mzy]], [[6mzu|6mzu]], [[6mzv|6mzv]], [[6n06|6n06]], [[6n07|6n07]], [[6n09|6n09]], [[6n0f|6n0f]], [[6n0g|6n0g]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6mzy|6mzy]], [[6mzu|6mzu]], [[6mzv|6mzv]], [[6n06|6n06]], [[6n07|6n07]], [[6n09|6n09]], [[6n0f|6n0f]], [[6n0g|6n0g]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Hoch_5814 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502025 HALO1]), Hoch_5815 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502025 HALO1]), Hoch_5816 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=502025 HALO1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mzx OCA], [http://pdbe.org/6mzx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mzx RCSB], [http://www.ebi.ac.uk/pdbsum/6mzx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mzx ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mzx OCA], [http://pdbe.org/6mzx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mzx RCSB], [http://www.ebi.ac.uk/pdbsum/6mzx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mzx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Bacterial microcompartments (BMCs) are composed of an enzymatic core encapsulated by a selectively permeable protein shell that enhances catalytic efficiency. Many pathogenic bacteria derive competitive advantages from their BMC-based catabolism, implicating BMCs as drug targets. BMC shells are of interest for bioengineering due to their diverse and selective permeability properties and because they self-assemble. A complete understanding of shell composition and organization is a prerequisite for biotechnological applications. Here, we report the cryoelectron microscopy structure of a BMC shell at 3.0-A resolution, using an image-processing strategy that allowed us to determine the previously uncharacterized structural details of the interactions formed by the BMC-T(S) and BMC-T(D) shell subunits in the context of the assembled shell. We found unexpected structural plasticity among these interactions, resulting in distinct shell populations assembled from varying numbers of the BMC-T(S) and BMC-T(D) subunits. We discuss the implications of these findings on shell assembly and function. | ||
| + | |||
| + | The Plasticity of Molecular Interactions Governs Bacterial Microcompartment Shell Assembly.,Greber BJ, Sutter M, Kerfeld CA Structure. 2019 Feb 12. pii: S0969-2126(19)30017-6. doi:, 10.1016/j.str.2019.01.017. PMID:30833088<ref>PMID:30833088</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6mzx" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Halo1]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Greber, B J]] | [[Category: Greber, B J]] | ||
Revision as of 08:28, 20 March 2019
Cryo-EM structure of the HO BMC shell: Icosahedral reconstruction (main population)
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