4cc6
From Proteopedia
(Difference between revisions)
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==Fragment-Based Discovery of 6 Azaindazoles As Inhibitors of Bacterial DNA Ligase== | ==Fragment-Based Discovery of 6 Azaindazoles As Inhibitors of Bacterial DNA Ligase== | ||
| - | <StructureSection load='4cc6' size='340' side='right' caption='[[4cc6]], [[Resolution|resolution]] 2.01Å' scene=''> | + | <StructureSection load='4cc6' size='340' side='right'caption='[[4cc6]], [[Resolution|resolution]] 2.01Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4cc6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CC6 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4cc6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CC6 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=L5Y:2-{[2-(1H-PYRAZOLO[3,4-C]PYRIDIN-3-YL)-6-(TRIFLUOROMETHYL)PYRIDIN-4-YL]AMINO}ETHANOL'>L5Y</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=L5Y:2-{[2-(1H-PYRAZOLO[3,4-C]PYRIDIN-3-YL)-6-(TRIFLUOROMETHYL)PYRIDIN-4-YL]AMINO}ETHANOL'>L5Y</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cc5|4cc5]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cc5|4cc5]]</td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4cc6" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4cc6" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[DNA ligase|DNA ligase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Amin, N]] | [[Category: Amin, N]] | ||
[[Category: Benowitz, A B]] | [[Category: Benowitz, A B]] | ||
Revision as of 08:55, 20 March 2019
Fragment-Based Discovery of 6 Azaindazoles As Inhibitors of Bacterial DNA Ligase
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Categories: Large Structures | Amin, N | Benowitz, A B | Chiarparin, E | Cui, H | Deng, X | Heightman, T D | Holmes, D J | Hopkins, A | Howard, S | Huang, J | Jin, Q | Kreatsoulas, C | Martin, A C.L | Massey, F | McCloskey, L | Mortenson, P N | Pathuri, P | Tisi, D | Williams, P A | Antibiotic design | Liga | Ligase
