2-oxoisovalerate dehydrogenase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 20: Line 20:
</StructureSection>
</StructureSection>
- 
-
==3D structures of 2-oxoisovalerate dehydrogenase==
 
- 
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
- 
-
[[2bp7]] - OIVD α+β subunits - ''Pseudomonas putida''<br />
 
-
[[1v1r]] - hOIVD α+β subunits - human<br />
 
-
[[1u5b]], [[1x80]], [[1ols]] - hOIVD α+β subunits + ThDP <br />
 
-
[[1x7x]], [[1x7w]], [[1x7y]], [[1x7z]], [[2j9f]], [[1olu]], [[2bfb]], [[2bfd]], [[2bfe]], [[1v11]] - hOIVD α (mutant)+ β subunits + ThDP derivative<br />
 
-
[[1olx]] - hOIVD α+β (mutant) subunits + ThDP<br />
 
-
[[1wci]] - hOIVD α+β subunits + thiamine derivative<br />
 
-
[[2bfe]] - hOIVD α+β subunits + pyrimidine derivative<br />
 
-
[[2bfc]] - hOIVD α (mutant)+ β subunits + pyrimidine derivative<br />
 
-
[[1v16]] - hOIVD α+β subunits + ThDP + benzamidine<br />
 
-
[[1v1m]] - hOIVD α (mutant)+ β subunits + ThDP + benzamidine<br />
 
-
[[2bew]], [[2beu]], [[2bev]] - hOIVD α+β subunits + ThDP derivative + peptide<br />
 
== References ==
== References ==

Revision as of 07:47, 21 March 2019

Human 2-oxoisovalerate dehydrogenase α (deepskyblue and cyan) and β (coral and orangered) subunit with phosphorylated Ser residue complex with thiamine diphosphate, glycerol, K+ ion (purple), Cl- ion (green) and Mn+2 ion (PDB code 1x80)

Drag the structure with the mouse to rotate

References

  1. ↑ Aevarsson A, Seger K, Turley S, Sokatch JR, Hol WG. Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes. Nat Struct Biol. 1999 Aug;6(8):785-92. PMID:10426958 doi:10.1038/11563
  2. ↑ Wang YP, Qi ML, Li TT, Zhao YJ. Two novel mutations in the BCKDHB gene (R170H, Q346R) cause the classic form of maple syrup urine disease (MSUD). Gene. 2012 Apr 25;498(1):112-5. doi: 10.1016/j.gene.2012.01.082. Epub 2012 Feb 3. PMID:22326532 doi:10.1016/j.gene.2012.01.082
  3. ↑ Wynn RM, Kato M, Machius M, Chuang JL, Li J, Tomchick DR, Chuang DT. Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation. Structure. 2004 Dec;12(12):2185-96. PMID:15576032 doi:10.1016/j.str.2004.09.013

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/2-oxoisovalerate_dehydrogenase"
Personal tools