5qgo
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with OX-220== | |
| - | + | <StructureSection load='5qgo' size='340' side='right'caption='[[5qgo]], [[Resolution|resolution]] 1.82Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5qgo]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QGO FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=H4A:(3aR,4R,6R,7R,8aR)-6-phenyloctahydro-1H-3a,7-epiminocyclohepta[c]pyrrol-4-ol'>H4A</scene></td></tr> | |
| - | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qgo OCA], [http://pdbe.org/5qgo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qgo RCSB], [http://www.ebi.ac.uk/pdbsum/5qgo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qgo ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NUDT7_HUMAN NUDT7_HUMAN]] Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'-phosphopantetheine. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Aimon, A]] | [[Category: Aimon, A]] | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Bradley, A R]] | ||
| + | [[Category: Brandao-Neto, J]] | ||
| + | [[Category: Brennan, P E]] | ||
| + | [[Category: Collins, P]] | ||
| + | [[Category: Delft, F von]] | ||
| + | [[Category: Douangamath, A]] | ||
| + | [[Category: Edwards, A]] | ||
[[Category: Elkins, J]] | [[Category: Elkins, J]] | ||
| - | [[Category: | + | [[Category: Fairhead, M]] |
[[Category: Huber, K]] | [[Category: Huber, K]] | ||
| - | [[Category: Ruda, G.F]] | ||
| - | [[Category: Arrowsmith, C.H]] | ||
| - | [[Category: Brandao-Neto, J]] | ||
| - | [[Category: Diaz Saez, L]] | ||
| - | [[Category: Fairhead, M]] | ||
| - | [[Category: Von Delft, F]] | ||
| - | [[Category: Bradley, A.R]] | ||
| - | [[Category: Talon, R]] | ||
| - | [[Category: Brennan, P.E]] | ||
| - | [[Category: Edwards, A]] | ||
| - | [[Category: Douangamath, A]] | ||
| - | [[Category: Szommer, T]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
| + | [[Category: London, N]] | ||
| + | [[Category: Nelson, A]] | ||
| + | [[Category: Ruda, G F]] | ||
| + | [[Category: Saez, L Diaz]] | ||
| + | [[Category: Spencer, J]] | ||
[[Category: Srikannathasan, V]] | [[Category: Srikannathasan, V]] | ||
| - | [[Category: | + | [[Category: Szommer, T]] |
| - | [[Category: | + | [[Category: Talon, R]] |
| - | [[Category: | + | [[Category: Hydrolase]] |
| + | [[Category: Nudix domain]] | ||
| + | [[Category: Pandda]] | ||
| + | [[Category: Sgc - diamond i04-1 fragment screening]] | ||
| + | [[Category: Xchemexplorer]] | ||
Revision as of 06:27, 27 March 2019
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with OX-220
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Categories: Large Structures | Aimon, A | Arrowsmith, C H | Bountra, C | Bradley, A R | Brandao-Neto, J | Brennan, P E | Collins, P | Delft, F von | Douangamath, A | Edwards, A | Elkins, J | Fairhead, M | Huber, K | Krojer, T | London, N | Nelson, A | Ruda, G F | Saez, L Diaz | Spencer, J | Srikannathasan, V | Szommer, T | Talon, R | Hydrolase | Nudix domain | Pandda | Sgc - diamond i04-1 fragment screening | Xchemexplorer
