6huf
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Coping with strong translational non-crystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a== | |
- | + | <StructureSection load='6huf' size='340' side='right'caption='[[6huf]], [[Resolution|resolution]] 2.82Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6huf]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HUF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HUF FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
- | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6huf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6huf OCA], [http://pdbe.org/6huf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6huf RCSB], [http://www.ebi.ac.uk/pdbsum/6huf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6huf ProSAT]</span></td></tr> |
- | [[Category: | + | </table> |
+ | == Disease == | ||
+ | [[http://www.uniprot.org/uniprot/RB27A_HUMAN RB27A_HUMAN]] Griscelli syndrome type 2. The disease is caused by mutations affecting the gene represented in this entry. | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/RB27A_HUMAN RB27A_HUMAN]] Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.<ref>PMID:18812475</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Cota, E]] | [[Category: Cota, E]] | ||
- | [[Category: Murray, J.W]] | ||
- | [[Category: Tate, E.W]] | ||
[[Category: Jamshidiha, M]] | [[Category: Jamshidiha, M]] | ||
+ | [[Category: Murray, J W]] | ||
[[Category: Perez-Dorado, I]] | [[Category: Perez-Dorado, I]] | ||
+ | [[Category: Read, R J]] | ||
+ | [[Category: Tate, E W]] | ||
+ | [[Category: Exocytosis]] | ||
+ | [[Category: Gtpase]] | ||
+ | [[Category: Vesicle transport]] |
Revision as of 06:39, 27 March 2019
Coping with strong translational non-crystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a
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