6gmp
From Proteopedia
(Difference between revisions)
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<StructureSection load='6gmp' size='340' side='right'caption='[[6gmp]], [[Resolution|resolution]] 1.35Å' scene=''> | <StructureSection load='6gmp' size='340' side='right'caption='[[6gmp]], [[Resolution|resolution]] 1.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[6gmp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GMP FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6gmp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Tryb2 Tryb2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GMP FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2mnt|2mnt]], [[2n87|2n87]], [[2n84|2n84]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2mnt|2mnt]], [[2n87|2n87]], [[2n84|2n84]]</td></tr> | ||
+ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tb927.7.2480 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=185431 TRYB2])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gmp OCA], [http://pdbe.org/6gmp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gmp RCSB], [http://www.ebi.ac.uk/pdbsum/6gmp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gmp ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gmp OCA], [http://pdbe.org/6gmp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gmp RCSB], [http://www.ebi.ac.uk/pdbsum/6gmp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gmp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | Trypanosoma brucei is a unicellular eukaryotic parasite, which causes the African sleeping sickness in humans. The recently discovered trypanosomal protein Parvulin 42 (TbPar42) plays a key role in parasite cell proliferation. Homologues of this two-domain protein are exclusively found in protozoa species. TbPar42 exhibits an N-terminal forkhead associated (FHA)-domain and a peptidyl-prolyl-cis/trans-isomerase (PPIase) domain, both connected by a linker. Using NMR and X-ray analysis as well as activity assays, we report on the structures of the single domains of TbPar42, discuss their intra-molecular interplay, and give some initial hints as to potential cellular functions of the protein. | ||
+ | |||
+ | Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei.,Rehic E, Hoenig D, Kamba BE, Goehring A, Hofmann E, Gasper R, Matena A, Bayer P Biomolecules. 2019 Mar 7;9(3). pii: biom9030093. doi: 10.3390/biom9030093. PMID:30866577<ref>PMID:30866577</ref> | ||
+ | |||
+ | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
+ | </div> | ||
+ | <div class="pdbe-citations 6gmp" style="background-color:#fffaf0;"></div> | ||
+ | == References == | ||
+ | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
+ | [[Category: Tryb2]] | ||
[[Category: Bayer, P]] | [[Category: Bayer, P]] | ||
[[Category: Gasper, R]] | [[Category: Gasper, R]] |
Revision as of 07:03, 27 March 2019
CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF TBPAR42
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Categories: Large Structures | Tryb2 | Bayer, P | Gasper, R | Hoenig, D | Hofmann, E | Rute, A | Isomerase | Ppiase