Baculoviral IAP repeat-containing protein

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<scene name='59/591978/Cv/3'>Zinc coordination site</scene> in human Baculoviral IAP repeat-containing protein 2 BIR3 domain (PDB code [[3d9t]])<ref>PMID:15657060</ref>
<scene name='59/591978/Cv/3'>Zinc coordination site</scene> in human Baculoviral IAP repeat-containing protein 2 BIR3 domain (PDB code [[3d9t]])<ref>PMID:15657060</ref>
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== 3D Structures of Baculoviral IAP repeat-containing protein ==
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[[Baculoviral IAP repeat-containing protein 3D structures]]
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</StructureSection>
</StructureSection>
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**[[5yud]] – mBIRC1e + flagellin – Cryo EM<br />
**[[5yud]] – mBIRC1e + flagellin – Cryo EM<br />
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*Baculoviral IAP repeat-containing protein 2 (cIAP1)
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*Baculoviral IAP repeat-containing protein 2 (cIAP1)); domains: BIR1 40-119; BIR3 266-363; CARD 435-562; RING 562-618
**[[3m1d]] – hcIAP1 BIR1 domain <br />
**[[3m1d]] – hcIAP1 BIR1 domain <br />
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**[[3mup]], [[3oz1]], [[4eb9]] – hcIAP1 BIR3 domain + SMAC-mimetic<br />
**[[3mup]], [[3oz1]], [[4eb9]] – hcIAP1 BIR3 domain + SMAC-mimetic<br />
**[[3uw4]] – hcIAP1 BIR3 domain (mutant) + anti-cancer peptide<br />
**[[3uw4]] – hcIAP1 BIR3 domain (mutant) + anti-cancer peptide<br />
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**[[6exw]] – hcIAP1 BIR3 domain (mutant) + azepine derivative<br />
**[[4hy4]], [[4hy5]], [[4lge]], [[4lgu]], [[4mti]], [[4mu7]], [[4kmn]], [[5m6n]] – hcIAP1 BIR3 domain + inhibitor<br />
**[[4hy4]], [[4hy5]], [[4lge]], [[4lgu]], [[4mti]], [[4mu7]], [[4kmn]], [[5m6n]] – hcIAP1 BIR3 domain + inhibitor<br />
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**[[6hpr]] – hcIAP1 RING domain + polyubiquitin + E2 ubiquitin-conjugating enzyme<br />
*Baculoviral IAP repeat-containing protein 3 (cIAP2)
*Baculoviral IAP repeat-containing protein 3 (cIAP2)

Revision as of 10:16, 1 April 2019

Human Baculoviral IAP repeat-containing protein 2 BIR3 domain (magenta) complex with caspase-9 peptide (green) and Zn+2 ion (PDB code 3d9t)

Drag the structure with the mouse to rotate

3D Structures of Baculoviral IAP repeat-containing protein

Updated on 01-April-2019

References

  1. Deveraux QL, Reed JC. IAP family proteins--suppressors of apoptosis. Genes Dev. 1999 Feb 1;13(3):239-52. PMID:9990849
  2. Raina D, Pandey P, Ahmad R, Bharti A, Ren J, Kharbanda S, Weichselbaum R, Kufe D. c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem. 2005 Mar 25;280(12):11147-51. Epub 2005 Jan 18. PMID:15657060 doi:10.1074/jbc.M413787200

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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