6jo3
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of (S)-3-O-geranylgeranylgryceryl phosphate synthase from Thermoplasma acidophilum in complex with substrate sn-glycerol-1-phosphate== | |
| - | + | <StructureSection load='6jo3' size='340' side='right'caption='[[6jo3]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6jo3]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5b69 5b69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JO3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1GP:SN-GLYCEROL-1-PHOSPHATE'>1GP</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mm1|4mm1]], [[2f6x|2f6x]]</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoglycerol_geranylgeranyltransferase Phosphoglycerol geranylgeranyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.41 2.5.1.41] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jo3 OCA], [http://pdbe.org/6jo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jo3 RCSB], [http://www.ebi.ac.uk/pdbsum/6jo3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jo3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GGGPS_THEAC GGGPS_THEAC]] Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. Cannot use sn-glycerol-3-phosphate (G3P) as substrate.<ref>PMID:12801917</ref> <ref>PMID:24684232</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Phosphoglycerol geranylgeranyltransferase]] | ||
| + | [[Category: Miyazono, K]] | ||
[[Category: Nemoto, N]] | [[Category: Nemoto, N]] | ||
| + | [[Category: Tanokura, M]] | ||
[[Category: Yamagishi, A]] | [[Category: Yamagishi, A]] | ||
| - | [[Category: | + | [[Category: Archaea]] |
| - | [[Category: | + | [[Category: Ether lipid]] |
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Thermoplasma]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 06:42, 3 April 2019
Crystal structure of (S)-3-O-geranylgeranylgryceryl phosphate synthase from Thermoplasma acidophilum in complex with substrate sn-glycerol-1-phosphate
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