5zgc

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'''Unreleased structure'''
 
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The entry 5zgc is ON HOLD until Paper Publication
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==Crystal Structure of SIRT3 in complex with H4K16bhb peptide==
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<StructureSection load='5zgc' size='340' side='right'caption='[[5zgc]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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Authors: Li, H., Zhang, X.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5zgc]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZGC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZGC FirstGlance]. <br>
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Description: Crystal Structure of SIRT3 in complex with H4K16bhb peptide
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KHB:'>KHB</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zgc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zgc OCA], [http://pdbe.org/5zgc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zgc RCSB], [http://www.ebi.ac.uk/pdbsum/5zgc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zgc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/SIR3_HUMAN SIR3_HUMAN]] NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.<ref>PMID:16788062</ref> <ref>PMID:18680753</ref> <ref>PMID:18794531</ref> <ref>PMID:19535340</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Li, H]]
[[Category: Li, H]]
[[Category: Zhang, X]]
[[Category: Zhang, X]]
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[[Category: Hydrolase]]
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[[Category: Rossmann fold]]

Revision as of 06:47, 3 April 2019

Crystal Structure of SIRT3 in complex with H4K16bhb peptide

PDB ID 5zgc

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