4ki7
From Proteopedia
(Difference between revisions)
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==Design and structural analysis of aromatic inhibitors of type II dehydroquinase from Mycobacterium tuberculosis - compound 41c [3-hydroxy-5-(3-nitrophenoxy)benzoic acid]== | ==Design and structural analysis of aromatic inhibitors of type II dehydroquinase from Mycobacterium tuberculosis - compound 41c [3-hydroxy-5-(3-nitrophenoxy)benzoic acid]== | ||
| - | <StructureSection load='4ki7' size='340' side='right' caption='[[4ki7]], [[Resolution|resolution]] 2.80Å' scene=''> | + | <StructureSection load='4ki7' size='340' side='right'caption='[[4ki7]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ki7]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KI7 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4ki7]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KI7 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1R2:3-HYDROXY-5-(3-NITROPHENOXY)BENZOIC+ACID'>1R2</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1R2:3-HYDROXY-5-(3-NITROPHENOXY)BENZOIC+ACID'>1R2</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroD, aroK, aroQ, MT2612, MTCY159.19, Rv2537c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ki7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ki7 OCA], [http://pdbe.org/4ki7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ki7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ki7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ki7 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ki7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ki7 OCA], [http://pdbe.org/4ki7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ki7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ki7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ki7 ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: 3-dehydroquinate dehydratase]] | [[Category: 3-dehydroquinate dehydratase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Abell, C]] | [[Category: Abell, C]] | ||
[[Category: Blundell, T L]] | [[Category: Blundell, T L]] | ||
Revision as of 08:49, 3 April 2019
Design and structural analysis of aromatic inhibitors of type II dehydroquinase from Mycobacterium tuberculosis - compound 41c [3-hydroxy-5-(3-nitrophenoxy)benzoic acid]
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