User:Sean Callahan/Sandbox 1
From Proteopedia
(Difference between revisions)
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
| - | == | + | == Structure == |
Although the hydrophobic pocket plays the major role in positioning the FAD cofactor and lysine substrate, <scene name='81/811711/Lysine_661/4'>Lysine 661 </scene> is a crucial, positively charged residue that is responsible for stabilizing FAD by creating a H-bond with | Although the hydrophobic pocket plays the major role in positioning the FAD cofactor and lysine substrate, <scene name='81/811711/Lysine_661/4'>Lysine 661 </scene> is a crucial, positively charged residue that is responsible for stabilizing FAD by creating a H-bond with | ||
===SWIRM Domain=== | ===SWIRM Domain=== | ||
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<scene name='81/811711/Regulator_loop/5'>Regulator Loop</scene> | <scene name='81/811711/Regulator_loop/5'>Regulator Loop</scene> | ||
This is the tower domain [[Image:Tower domain.png|400 px|right|thumb|Figure 1]] | This is the tower domain [[Image:Tower domain.png|400 px|right|thumb|Figure 1]] | ||
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| + | <scene name='81/811710/Oxidase/1'>Oxidase Domain</scene> | ||
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== Disease == | == Disease == | ||
Revision as of 17:12, 5 April 2019
=Lysine Specific Demethylase 1 (Homo sapiens)=
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
- ↑ Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677
- ↑ Mineo R, Sharrock NE. Venous levels of lidocaine and bupivacaine after midtarsal ankle block. Reg Anesth. 1992 Jan-Feb;17(1):47-9. PMID:1599895
