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5qi8

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'''Unreleased structure'''
 
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The entry 5qi8 is ON HOLD
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==PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000605a==
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<StructureSection load='5qi8' size='340' side='right'caption='[[5qi8]], [[Resolution|resolution]] 1.09&Aring;' scene=''>
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Authors: Schuller, M., Talon, R., Krojer, T., Brandao-Neto, J., Douangamath, A., Zhang, R., von Delft, F., Schuler, H., Kessler, B., Knapp, S., Bountra, C., Arrowsmith, C.H., Edwards, A., Elkins, J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qi8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QI8 FirstGlance]. <br>
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Description: PanDDA analysis group deposition --Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000605a
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GVY:4-(5-amino-1,3,4-thiadiazol-2-yl)phenol'>GVY</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qi8 OCA], [http://pdbe.org/5qi8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qi8 RCSB], [http://www.ebi.ac.uk/pdbsum/5qi8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qi8 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PAR14_HUMAN PAR14_HUMAN]] Enhances STAT6-dependent transcription (By similarity). Has ADP-ribosyltransferase activity.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Brandao-Neto, J]]
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[[Category: Delft, F von]]
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[[Category: Douangamath, A]]
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[[Category: Edwards, A]]
[[Category: Elkins, J]]
[[Category: Elkins, J]]
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[[Category: Zhang, R]]
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[[Category: Kessler, B]]
[[Category: Knapp, S]]
[[Category: Knapp, S]]
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[[Category: Arrowsmith, C.H]]
 
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[[Category: Brandao-Neto, J]]
 
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[[Category: Talon, R]]
 
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[[Category: Edwards, A]]
 
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[[Category: Douangamath, A]]
 
[[Category: Krojer, T]]
[[Category: Krojer, T]]
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[[Category: Kessler, B]]
 
[[Category: Schuler, H]]
[[Category: Schuler, H]]
[[Category: Schuller, M]]
[[Category: Schuller, M]]
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[[Category: Von Delft, F]]
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[[Category: Talon, R]]
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[[Category: Bountra, C]]
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[[Category: Zhang, R]]
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[[Category: Macrodomain]]
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[[Category: Pandda]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Transferase]]
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[[Category: Xchemexplorer]]

Revision as of 07:04, 10 April 2019

PanDDA analysis group deposition -- Crystal Structure of human PARP14 Macrodomain 3 in complex with FMOPL000605a

PDB ID 5qi8

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