This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6d07
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the complex between human chromobox homolog 1 (CBX1) and H3K9me3 peptide== | |
| - | + | <StructureSection load='6d07' size='340' side='right'caption='[[6d07]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6d07]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D07 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D07 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6d08|6d08]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d07 OCA], [http://pdbe.org/6d07 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d07 RCSB], [http://www.ebi.ac.uk/pdbsum/6d07 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d07 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CBX1_HUMAN CBX1_HUMAN]] Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arora, S]] | ||
| + | [[Category: Horne, W S]] | ||
| + | [[Category: Islam, K]] | ||
| + | [[Category: Bump-hole]] | ||
| + | [[Category: Chromodomain]] | ||
| + | [[Category: Epigenetic]] | ||
| + | [[Category: Lysine modification]] | ||
| + | [[Category: Protein binding]] | ||
Revision as of 07:10, 10 April 2019
Crystal structure of the complex between human chromobox homolog 1 (CBX1) and H3K9me3 peptide
| |||||||||||
