6d07
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the complex between human chromobox homolog 1 (CBX1) and H3K9me3 peptide== | |
| - | + | <StructureSection load='6d07' size='340' side='right'caption='[[6d07]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6d07]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D07 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D07 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6d08|6d08]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d07 OCA], [http://pdbe.org/6d07 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d07 RCSB], [http://www.ebi.ac.uk/pdbsum/6d07 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d07 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CBX1_HUMAN CBX1_HUMAN]] Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arora, S]] | ||
| + | [[Category: Horne, W S]] | ||
| + | [[Category: Islam, K]] | ||
| + | [[Category: Bump-hole]] | ||
| + | [[Category: Chromodomain]] | ||
| + | [[Category: Epigenetic]] | ||
| + | [[Category: Lysine modification]] | ||
| + | [[Category: Protein binding]] | ||
Revision as of 07:10, 10 April 2019
Crystal structure of the complex between human chromobox homolog 1 (CBX1) and H3K9me3 peptide
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