6g23

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'''Unreleased structure'''
 
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The entry 6g23 is ON HOLD
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==Phosphotriesterase PTE_C23M_2==
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<StructureSection load='6g23' size='340' side='right'caption='[[6g23]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
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Authors: Dym, O., Aggarwal, N., Albeck, S., Unger, T., Hamer Rogotner, S., Silman, I., Leader, H., Ashani, Y., Goldsmith, M., Greisen, P., Tawfik, D., Sussman, L.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6g23]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G23 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G23 FirstGlance]. <br>
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Description: Phosphotriesterase PTE_C23M_2
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E8N:1-ethyl-1-methyl-cyclohexane'>E8N</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=FU2:FURFURAL'>FU2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6g1j|6g1j]]</td></tr>
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[[Category: Leader, H]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] </span></td></tr>
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[[Category: Sussman, L.J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g23 OCA], [http://pdbe.org/6g23 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g23 RCSB], [http://www.ebi.ac.uk/pdbsum/6g23 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g23 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/OPD_BREDI OPD_BREDI]] Has an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates. All of the phosphate triesters found to be substrates are synthetic compounds. The identity of any naturally occurring substrate for the enzyme is unknown. Has no detectable activity with phosphate monoesters or diesters and no activity as an esterase or protease. It catalyzes the hydrolysis of the insecticide paraoxon at a rate approaching the diffusion limit and thus appears to be optimally evolved for utilizing this synthetic substrate.
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__TOC__
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</StructureSection>
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[[Category: Aryldialkylphosphatase]]
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[[Category: Large Structures]]
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[[Category: Aggarwal, N]]
[[Category: Albeck, S]]
[[Category: Albeck, S]]
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[[Category: Unger, T]]
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[[Category: Ashani, Y]]
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[[Category: Aggarwal, N]]
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[[Category: Dym, O]]
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[[Category: Goldsmith, M]]
[[Category: Greisen, P]]
[[Category: Greisen, P]]
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[[Category: Goldsmith, M]]
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[[Category: Leader, H]]
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[[Category: Hamer Rogotner, S]]
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[[Category: Rogotner, S Hamer]]
[[Category: Silman, I]]
[[Category: Silman, I]]
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[[Category: Sussman, L J]]
[[Category: Tawfik, D]]
[[Category: Tawfik, D]]
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[[Category: Ashani, Y]]
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[[Category: Unger, T]]
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[[Category: Dym, O]]
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[[Category: Hydrolase]]
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[[Category: Metalloenzyme]]
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[[Category: Tim barrel]]

Revision as of 07:15, 10 April 2019

Phosphotriesterase PTE_C23M_2

PDB ID 6g23

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