6qt9

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m (Protected "6qt9" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6qt9 is ON HOLD
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==Cryo-EM structure of SH1 full particle.==
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<StructureSection load='6qt9' size='340' side='right'caption='[[6qt9]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6qt9]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_hispanica_virus_sh1 Haloarcula hispanica virus sh1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QT9 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qt9 OCA], [http://pdbe.org/6qt9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qt9 RCSB], [http://www.ebi.ac.uk/pdbsum/6qt9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qt9 ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Many of the largest known viruses belong to the PRD1-adeno structural lineage characterised by conserved pseudo-hexameric capsomers composed of three copies of a single major capsid protein (MCP). Here, by high-resolution cryo-EM analysis, we show that a class of archaeal viruses possess hetero-hexameric MCPs which mimic the PRD1-adeno lineage trimer. These hetero-hexamers are built from heterodimers and utilise a jigsaw-puzzle system of pegs and holes, and underlying minor capsid proteins, to assemble the capsid laterally from the 5-fold vertices. At these vertices proteins engage inwards with the internal membrane vesicle whilst 2-fold symmetric horn-like structures protrude outwards. The horns are assembled from repeated globular domains attached to a central spine, presumably facilitating multimeric attachment to the cell receptor. Such viruses may represent precursors of the main PRD1-adeno lineage, similarly engaging cell-receptors via 5-fold spikes and using minor proteins to define particle size.
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Authors: De Colibus, L., Roine, E., Walter, T.S., Ilca, S.L., Wang, X., Wang, N., Roseman, A.M., Bamford, D., Huiskonen, J.T., Stuart, D.I.
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Assembly of complex viruses exemplified by a halophilic euryarchaeal virus.,Colibus L, Roine E, Walter TS, Ilca SL, Wang X, Wang N, Roseman AM, Bamford D, Huiskonen JT, Stuart DI Nat Commun. 2019 Mar 29;10(1):1456. doi: 10.1038/s41467-019-09451-z. PMID:30926810<ref>PMID:30926810</ref>
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Description: Cryo-EM structure of SH1 full particle.
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Unreleased Structures]]
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</div>
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[[Category: Walter, T.S]]
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<div class="pdbe-citations 6qt9" style="background-color:#fffaf0;"></div>
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[[Category: Roseman, A.M]]
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== References ==
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[[Category: Roine, E]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Haloarcula hispanica virus sh1]]
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[[Category: Large Structures]]
[[Category: Bamford, D]]
[[Category: Bamford, D]]
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[[Category: Ilca, S.L]]
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[[Category: Colibus, L De]]
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[[Category: Huiskonen, J.T]]
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[[Category: Huiskonen, J T]]
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[[Category: Ilca, S L]]
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[[Category: Roine, E]]
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[[Category: Roseman, A M]]
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[[Category: Stuart, D I]]
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[[Category: Walter, T S]]
[[Category: Wang, N]]
[[Category: Wang, N]]
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[[Category: De Colibus, L]]
 
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[[Category: Stuart, D.I]]
 
[[Category: Wang, X]]
[[Category: Wang, X]]
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[[Category: Euryarcheal virus]]
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[[Category: Sh1]]
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[[Category: Virus]]

Revision as of 07:30, 10 April 2019

Cryo-EM structure of SH1 full particle.

PDB ID 6qt9

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