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5dtj
From Proteopedia
(Difference between revisions)
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==Crystal Structure of dfp-inhibited mouse acetylcholinesterase in complex with the reactivator SP-134== | ==Crystal Structure of dfp-inhibited mouse acetylcholinesterase in complex with the reactivator SP-134== | ||
| - | <StructureSection load='5dtj' size='340' side='right' caption='[[5dtj]], [[Resolution|resolution]] 2.71Å' scene=''> | + | <StructureSection load='5dtj' size='340' side='right'caption='[[5dtj]], [[Resolution|resolution]] 2.71Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5dtj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DTJ FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5dtj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DTJ FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5G8:1-[5-(2,4-DICHLOROPHENOXY)PENTYL]-1H-IMIDAZOLE'>5G8</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5G8:1-[5-(2,4-DICHLOROPHENOXY)PENTYL]-1H-IMIDAZOLE'>5G8</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MIS:MONOISOPROPYLPHOSPHORYLSERINE'>MIS</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MIS:MONOISOPROPYLPHOSPHORYLSERINE'>MIS</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dtg|5dtg]], [[5dti|5dti]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dtg|5dtg]], [[5dti|5dti]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ache ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dtj OCA], [http://pdbe.org/5dtj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dtj RCSB], [http://www.ebi.ac.uk/pdbsum/5dtj PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dtj OCA], [http://pdbe.org/5dtj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dtj RCSB], [http://www.ebi.ac.uk/pdbsum/5dtj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dtj ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5dtj" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5dtj" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lk3 transgenic mice]] | ||
[[Category: Tong, L]] | [[Category: Tong, L]] | ||
[[Category: Tran, T H]] | [[Category: Tran, T H]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 07:38, 10 April 2019
Crystal Structure of dfp-inhibited mouse acetylcholinesterase in complex with the reactivator SP-134
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