6fh1
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Protein arginine kinase McsB in the apo state== | |
| + | <StructureSection load='6fh1' size='340' side='right'caption='[[6fh1]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6fh1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FH1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FH1 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mcsB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 ATCC 12980])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein_arginine_kinase Protein arginine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.14.1 2.7.14.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fh1 OCA], [http://pdbe.org/6fh1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fh1 RCSB], [http://www.ebi.ac.uk/pdbsum/6fh1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fh1 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MCSB_GEOSE MCSB_GEOSE]] Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system, where it is involved in regulating the global heat shock repressor CtsR; phosphorylates arginine residues in the winged helix-turn-helix domain of CtsR, thereby preventing its binding to DNA and consequently inducing the expression of repressed genes. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. Acts exclusively on Arg residues, since it cannot phosphorylate Tyr, Ser, Thr, His, Asp and Lys.<ref>PMID:19498169</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Arginine kinase 3D structures|Arginine kinase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Atcc 12980]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Protein arginine kinase]] | ||
| + | [[Category: Clausen, T]] | ||
| + | [[Category: Heuck, A]] | ||
| + | [[Category: Suskiewicz, M J]] | ||
| + | [[Category: Vu, L D]] | ||
| + | [[Category: Phospho-binding domain]] | ||
| + | [[Category: Protein arginine phosphorylation]] | ||
| + | [[Category: Protein kinase]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 07:48, 10 April 2019
Protein arginine kinase McsB in the apo state
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