4mdd
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the Glucocorticoid Receptor Bound to a Non-steroidal Antagonist Reveals Repositioning and Partial Disordering of Activation Function Helix 12== | ==Crystal Structure of the Glucocorticoid Receptor Bound to a Non-steroidal Antagonist Reveals Repositioning and Partial Disordering of Activation Function Helix 12== | ||
| - | <StructureSection load='4mdd' size='340' side='right' caption='[[4mdd]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='4mdd' size='340' side='right'caption='[[4mdd]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4mdd]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MDD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MDD FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4mdd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MDD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MDD FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=29M:N-[2-{[BENZYL(METHYL)AMINO]METHYL}-3-(4-FLUORO-2-METHOXYPHENYL)-5-(PROPAN-2-YL)-1H-INDOL-7-YL]METHANESULFONAMIDE'>29M</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=29M:N-[2-{[BENZYL(METHYL)AMINO]METHYL}-3-(4-FLUORO-2-METHOXYPHENYL)-5-(PROPAN-2-YL)-1H-INDOL-7-YL]METHANESULFONAMIDE'>29M</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NR3C1, GRL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mdd OCA], [http://pdbe.org/4mdd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mdd RCSB], [http://www.ebi.ac.uk/pdbsum/4mdd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mdd ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mdd OCA], [http://pdbe.org/4mdd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mdd RCSB], [http://www.ebi.ac.uk/pdbsum/4mdd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mdd ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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==See Also== | ==See Also== | ||
*[[Glucocorticoid receptor|Glucocorticoid receptor]] | *[[Glucocorticoid receptor|Glucocorticoid receptor]] | ||
| + | *[[Nuclear receptor corepressor|Nuclear receptor corepressor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Coghlan, M J]] | [[Category: Coghlan, M J]] | ||
[[Category: Luz, J G]] | [[Category: Luz, J G]] | ||
[[Category: Nuclear hormone receptor ligand binding domain]] | [[Category: Nuclear hormone receptor ligand binding domain]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
Revision as of 08:43, 10 April 2019
Crystal Structure of the Glucocorticoid Receptor Bound to a Non-steroidal Antagonist Reveals Repositioning and Partial Disordering of Activation Function Helix 12
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