4nns
From Proteopedia
(Difference between revisions)
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==Crystal structure of FABP4 in complex with novel inhibitor== | ==Crystal structure of FABP4 in complex with novel inhibitor== | ||
| - | <StructureSection load='4nns' size='340' side='right' caption='[[4nns]], [[Resolution|resolution]] 1.53Å' scene=''> | + | <StructureSection load='4nns' size='340' side='right'caption='[[4nns]], [[Resolution|resolution]] 1.53Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nns]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNS FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4nns]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNS FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=75D:2,4,6-TRI(PROPAN-2-YL)BENZENESULFONIC+ACID'>75D</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=75D:2,4,6-TRI(PROPAN-2-YL)BENZENESULFONIC+ACID'>75D</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nnt|4nnt]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nnt|4nnt]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FABP4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nns OCA], [http://pdbe.org/4nns PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nns RCSB], [http://www.ebi.ac.uk/pdbsum/4nns PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nns ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nns FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nns OCA], [http://pdbe.org/4nns PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nns RCSB], [http://www.ebi.ac.uk/pdbsum/4nns PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nns ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN]] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). | [[http://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN]] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity). | ||
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| + | ==See Also== | ||
| + | *[[Fatty acid-binding protein|Fatty acid-binding protein]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Chen, T T]] | [[Category: Chen, T T]] | ||
[[Category: Liu, Q F]] | [[Category: Liu, Q F]] | ||
Revision as of 08:57, 10 April 2019
Crystal structure of FABP4 in complex with novel inhibitor
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