Blue copper oxidase CueO
From Proteopedia
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== Function == | == Function == | ||
- | '''Blue copper oxidase CueO''' (CueO) is an ''E. coli'' enzyme which catalyzes the conversion of Cu+1 to Cu+2 resulting in the detoxification of copper by the prevention of its uptake into the cytoplasm.<ref>PMID:11527384</ref> | + | '''Blue copper oxidase CueO''' (CueO) or '''laccase CueO''' is an ''E. coli'' enzyme which catalyzes the conversion of Cu+1 to Cu+2 resulting in the detoxification of copper by the prevention of its uptake into the cytoplasm.<ref>PMID:11527384</ref> |
== Relevance == | == Relevance == |
Revision as of 10:20, 14 April 2019
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3D structures of blue copper oxidase CueO
Updated on 14-April-2019
3nsf – EcCueO – Escherichia coli
3nt0 – EcCueO (mutant) + Cu+1
3od3, 3pav, 4e9q, 4e9r, 4e9s, 4e9t, 4ef3, 4ner, 5b7e, 5b7f, 5b7m – EcCueO + Cu+2
3nsc, 3nsd, 3uaa, 3uab, 3uac, 3uad, 3uae, 4hak, 4hal – EcCueO (mutant) + Cu+2
3qqx – EcCueO (mutant) + Cu+2 + Cu+1
1n68 – EcCueO + Cu+2 + Cu-Cl-Cu
1pf3 – EcCueO (mutant) + Cu+2 + Cu-Cl-Cu
2fqd, 2fqe, 2fqf, 2fqg, 3pau – EcCueO + Cu+2 + Cu-O-Cu
2yxv, 2yxw, 3nsy – EcCueO (mutant) + Cu+2 + Cu-O-Cu
References
- ↑ Grass G, Rensing C. CueO is a multi-copper oxidase that confers copper tolerance in Escherichia coli. Biochem Biophys Res Commun. 2001 Sep 7;286(5):902-8. PMID:11527384 doi:http://dx.doi.org/10.1006/bbrc.2001.5474
- ↑ Li X, Wei Z, Zhang M, Peng X, Yu G, Teng M, Gong W. Crystal structures of E. coli laccase CueO at different copper concentrations. Biochem Biophys Res Commun. 2007 Mar 2;354(1):21-6. Epub 2006 Dec 22. PMID:17217912 doi:10.1016/j.bbrc.2006.12.116