BRCA
From Proteopedia
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== Structural highlights == | == Structural highlights == | ||
The <scene name='75/750267/Cv/5'>phosphopeptide binds at the interface between the BRCT1 and BRCT2 domains</scene>. These domains contain most of the mutations seen in BRCA1<ref>PMID:18452305</ref>. <scene name='75/750267/Cv/6'>Phosphoserine binding</scene>. | The <scene name='75/750267/Cv/5'>phosphopeptide binds at the interface between the BRCT1 and BRCT2 domains</scene>. These domains contain most of the mutations seen in BRCA1<ref>PMID:18452305</ref>. <scene name='75/750267/Cv/6'>Phosphoserine binding</scene>. | ||
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| + | ==3D structures of BRCA== | ||
| + | [[BRCA 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
Revision as of 09:56, 16 April 2019
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3D structures of BRCA
Updated on 16-April-2019
References
- ↑ Petrucelli N, Daly MB, Pal T. BRCA1- and BRCA2-Associated Hereditary Breast and Ovarian Cancer PMID:20301425
- ↑ Shen Y, Tong L. Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1. Biochemistry. 2008 May 27;47(21):5767-73. Epub 2008 May 2. PMID:18452305 doi:10.1021/bi800314m
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