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| - | | + | #REDIRECT [[6qjf]] This PDB entry is obsolete and replaced by 6qjf |
| - | ==Crystal Structure of the third PDZ domain of PSD-95 protein D332P mutant: space group C121, structure 1==
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| - | <StructureSection load='5oi4' size='340' side='right' caption='[[5oi4]], [[Resolution|resolution]] 1.50Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[5oi4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OI4 FirstGlance]. <br>
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| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oi4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oi4 OCA], [http://pdbe.org/5oi4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oi4 RCSB], [http://www.ebi.ac.uk/pdbsum/5oi4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oi4 ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/DLG4_HUMAN DLG4_HUMAN]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Camara-Artigas, A]]
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| - | [[Category: Pdz domain]]
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| - | [[Category: Signaling protein]]
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Current revision
- REDIRECT 6qjf This PDB entry is obsolete and replaced by 6qjf
