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| - | | + | #REDIRECT [[6qjn]] This PDB entry is obsolete and replaced by 6qjn |
| - | ==Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group I4122==
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| - | <StructureSection load='5oij' size='340' side='right' caption='[[5oij]], [[Resolution|resolution]] 1.80Å' scene=''>
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| - | == Structural highlights ==
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| - | <table><tr><td colspan='2'>[[5oij]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OIJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OIJ FirstGlance]. <br>
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| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oij OCA], [http://pdbe.org/5oij PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oij RCSB], [http://www.ebi.ac.uk/pdbsum/5oij PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oij ProSAT]</span></td></tr>
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| - | </table>
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| - | == Function ==
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| - | [[http://www.uniprot.org/uniprot/DLG4_HUMAN DLG4_HUMAN]] Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
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| - | __TOC__
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| - | </StructureSection>
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| - | [[Category: Camara-Artigas, A]]
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| - | [[Category: Pdz domain]]
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| - | [[Category: Signaling protein]]
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Current revision
- REDIRECT 6qjn This PDB entry is obsolete and replaced by 6qjn
