6hzl
From Proteopedia
(Difference between revisions)
| Line 9: | Line 9: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hzl OCA], [http://pdbe.org/6hzl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hzl RCSB], [http://www.ebi.ac.uk/pdbsum/6hzl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hzl ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hzl OCA], [http://pdbe.org/6hzl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hzl RCSB], [http://www.ebi.ac.uk/pdbsum/6hzl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hzl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Phosphoribulokinase (PRK) catalyses the ATP-dependent phosphorylation of ribulose 5-phosphate to give ribulose 1,5-bisphosphate. Regulation of this reaction in response to light controls carbon fixation during photosynthesis. Here, the crystal structure of PRK from the cyanobacterium Synechococcus sp. strain PCC 6301 is presented. The enzyme is dimeric and has an alpha/beta-fold with an 18-stranded beta-sheet at its core. Interestingly, a disulfide bond is found between Cys40 and the P-loop residue Cys18, revealing the structural basis for the redox inactivation of PRK activity. A second disulfide bond appears to rigidify the dimer interface and may thereby contribute to regulation by the adaptor protein CP12 and glyceraldehyde-3-phosphate dehydrogenase. | ||
| + | |||
| + | Crystal structure of phosphoribulokinase from Synechococcus sp. strain PCC 6301.,Wilson RH, Hayer-Hartl M, Bracher A Acta Crystallogr F Struct Biol Commun. 2019 Apr 1;75(Pt 4):278-289. doi:, 10.1107/S2053230X19002693. Epub 2019 Apr 2. PMID:30950829<ref>PMID:30950829</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6hzl" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Crystal structure of redox-inhibited phosphoribulokinase from Synechococcus sp. (strain PCC 6301), osmate derivative
| |||||||||||
