4p90
From Proteopedia
(Difference between revisions)
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==Crystal structure of the kinase domain of human PAK1 in complex with compound 15== | ==Crystal structure of the kinase domain of human PAK1 in complex with compound 15== | ||
- | <StructureSection load='4p90' size='340' side='right' caption='[[4p90]], [[Resolution|resolution]] 2.49Å' scene=''> | + | <StructureSection load='4p90' size='340' side='right'caption='[[4p90]], [[Resolution|resolution]] 2.49Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4p90]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P90 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4p90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P90 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2K0:[2-CHLORO-5-(HYDROXYMETHYL)PHENYL]{5-[1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}METHANONE'>2K0</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2K0:[2-CHLORO-5-(HYDROXYMETHYL)PHENYL]{5-[1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL]-1H-PYRROLO[2,3-B]PYRIDIN-3-YL}METHANONE'>2K0</scene></td></tr> | ||
+ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PAK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p90 OCA], [http://pdbe.org/4p90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p90 RCSB], [http://www.ebi.ac.uk/pdbsum/4p90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p90 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p90 OCA], [http://pdbe.org/4p90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p90 RCSB], [http://www.ebi.ac.uk/pdbsum/4p90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p90 ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Human]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Ferguson, A D]] | [[Category: Ferguson, A D]] |
Revision as of 07:35, 17 April 2019
Crystal structure of the kinase domain of human PAK1 in complex with compound 15
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