Calreticulin

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Current revision (10:06, 21 April 2019) (edit) (undo)
 
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== 3D Structures of calreticulin ==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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[[1hhn]], [[1k91]], [[1k9c]] – CALR P domain 189-288 – rat - NMR <br />
 
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[[6eny]] – hCALR + β-microglobulin + tapasin + protein disulfide-isomerase + MHC class I antigen – human <br />
 
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[[5v90]] – hCALR P domain 238-273 + ERP29 <br />
 
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[[3o0v]], [[3o0w]], [[3o0x]], [[3rg0]] – CALR lectin domain 18-206 301-368 (mutant) – mouse <br />
 
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[[3pos]], [[3pow]] – hCALR lectin domain 18-206 301-368 <br />
 
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[[5lk5]] – hCALR lectin domain 18-206 301-368 (mutant) <br />
 
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[[5hca]], [[5hcb]] – CALR lectin domain 18-206 301-368 + glucose – ''Entamoeba histolytica'' <br />
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Human calreticulin (gold) complex with β-microglobulin (green), tapasin (pink), protein disulfide-isomerase (yellow) MHC class I antigen (cyan) (PDB code 6eny)

Drag the structure with the mouse to rotate

References

  1. Coppolino MG, Dedhar S. Calreticulin. Int J Biochem Cell Biol. 1998 May;30(5):553-8. PMID:9693955
  2. Klampfl T, Gisslinger H, Harutyunyan AS, Nivarthi H, Rumi E, Milosevic JD, Them NC, Berg T, Gisslinger B, Pietra D, Chen D, Vladimer GI, Bagienski K, Milanesi C, Casetti IC, Sant'Antonio E, Ferretti V, Elena C, Schischlik F, Cleary C, Six M, Schalling M, Schonegger A, Bock C, Malcovati L, Pascutto C, Superti-Furga G, Cazzola M, Kralovics R. Somatic mutations of calreticulin in myeloproliferative neoplasms. N Engl J Med. 2013 Dec 19;369(25):2379-90. doi: 10.1056/NEJMoa1311347. Epub 2013 , Dec 10. PMID:24325356 doi:http://dx.doi.org/10.1056/NEJMoa1311347
  3. Wang WA, Groenendyk J, Michalak M. Calreticulin signaling in health and disease. Int J Biochem Cell Biol. 2012 Jun;44(6):842-6. doi: 10.1016/j.biocel.2012.02.009., Epub 2012 Feb 21. PMID:22373697 doi:http://dx.doi.org/10.1016/j.biocel.2012.02.009

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