6nxf

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m (Protected "6nxf" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6nxf is ON HOLD until Paper Publication
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==Crystal structure of mouse REC114 PH domain in complex with ANKRD31 C terminus==
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<StructureSection load='6nxf' size='340' side='right'caption='[[6nxf]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6nxf]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NXF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6NXF FirstGlance]. <br>
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Description:
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6nxf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nxf OCA], [http://pdbe.org/6nxf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nxf RCSB], [http://www.ebi.ac.uk/pdbsum/6nxf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nxf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/RE114_MOUSE RE114_MOUSE]] Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination (PubMed:20551173, PubMed:27723721). Probably acts by forming a complex with IHO1/CCDC36 and MEI4, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis (PubMed:27723721).<ref>PMID:20551173</ref> <ref>PMID:27723721</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Patel, D J]]
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[[Category: Wang, J]]
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[[Category: Ankrd31]]
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[[Category: Meiosis]]
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[[Category: Nuclear protein]]
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[[Category: Rec114]]

Revision as of 07:03, 24 April 2019

Crystal structure of mouse REC114 PH domain in complex with ANKRD31 C terminus

PDB ID 6nxf

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