6hm0
From Proteopedia
(Difference between revisions)
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==Crystal structure of human BRD9 bromodomain in complex with a PROTAC== | ==Crystal structure of human BRD9 bromodomain in complex with a PROTAC== | ||
| - | <StructureSection load='6hm0' size='340' side='right' caption='[[6hm0]], [[Resolution|resolution]] 2.40Å' scene=''> | + | <StructureSection load='6hm0' size='340' side='right'caption='[[6hm0]], [[Resolution|resolution]] 2.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6hm0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HM0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HM0 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6hm0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HM0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HM0 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GBW:(2~{S},4~{S})-1-[(2~{S})-2-[2-[2-[2-[4-[[2,6-dimethoxy-4-(2-methyl-1-oxidanylidene-2,7-naphthyridin-4-yl)phenyl]methyl]piperazin-1-yl]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide'>GBW</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GBW:(2~{S},4~{S})-1-[(2~{S})-2-[2-[2-[2-[4-[[2,6-dimethoxy-4-(2-methyl-1-oxidanylidene-2,7-naphthyridin-4-yl)phenyl]methyl]piperazin-1-yl]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide'>GBW</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD9, UNQ3040/PRO9856 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hm0 OCA], [http://pdbe.org/6hm0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hm0 RCSB], [http://www.ebi.ac.uk/pdbsum/6hm0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hm0 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hm0 OCA], [http://pdbe.org/6hm0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hm0 RCSB], [http://www.ebi.ac.uk/pdbsum/6hm0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hm0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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</div> | </div> | ||
<div class="pdbe-citations 6hm0" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6hm0" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Ciulli, A]] | [[Category: Ciulli, A]] | ||
[[Category: Hughes, S J]] | [[Category: Hughes, S J]] | ||
Revision as of 07:57, 24 April 2019
Crystal structure of human BRD9 bromodomain in complex with a PROTAC
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