This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4qx4
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Human Aldose Reductase complexed with a ligand with a new scaffold at 1.26 A== | ==Human Aldose Reductase complexed with a ligand with a new scaffold at 1.26 A== | ||
| - | <StructureSection load='4qx4' size='340' side='right' caption='[[4qx4]], [[Resolution|resolution]] 1.26Å' scene=''> | + | <StructureSection load='4qx4' size='340' side='right'caption='[[4qx4]], [[Resolution|resolution]] 1.26Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4qx4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QX4 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4qx4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QX4 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3E2:(3-THIOXO-2,3-DIHYDRO-5H-[1,2,4]TRIAZINO[5,6-B]INDOL-5-YL)ACETIC+ACID'>3E2</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3E2:(3-THIOXO-2,3-DIHYDRO-5H-[1,2,4]TRIAZINO[5,6-B]INDOL-5-YL)ACETIC+ACID'>3E2</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1us0|1us0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1us0|1us0]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qx4 OCA], [http://pdbe.org/4qx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qx4 RCSB], [http://www.ebi.ac.uk/pdbsum/4qx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qx4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qx4 OCA], [http://pdbe.org/4qx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qx4 RCSB], [http://www.ebi.ac.uk/pdbsum/4qx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qx4 ProSAT]</span></td></tr> | ||
| Line 22: | Line 23: | ||
==See Also== | ==See Also== | ||
| - | *[[Aldose | + | *[[Aldose reductase 3D structures|Aldose reductase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
| Line 28: | Line 29: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Heine, A]] | [[Category: Heine, A]] | ||
[[Category: Klebe, G]] | [[Category: Klebe, G]] | ||
Revision as of 09:13, 24 April 2019
Human Aldose Reductase complexed with a ligand with a new scaffold at 1.26 A
| |||||||||||
