4r09
From Proteopedia
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==Crystal structure of human TLR8 in complex with ORN06S== | ==Crystal structure of human TLR8 in complex with ORN06S== | ||
| - | <StructureSection load='4r09' size='340' side='right' caption='[[4r09]], [[Resolution|resolution]] 2.62Å' scene=''> | + | <StructureSection load='4r09' size='340' side='right'caption='[[4r09]], [[Resolution|resolution]] 2.62Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4r09]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R09 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R09 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4r09]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R09 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R09 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=06S:O-[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)-2-({[(S)-({(2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-HYDROXY-2-[(THIOPHOSPHONOOXY)METHYL]TETRAHYDROFURAN-3-YL}OXY)(SULFANYL)PHOSPHORYL]OXY}METHYL)-4-HYDROXYTETRAHYDROFURAN-3-YL]+DIHYDROGEN+(S)-PHOSPHOROTHIOATE'>06S</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=UPT:1-[(2R,3AR,4R,6R,6AR)-2-HYDROXY-6-(HYDROXYMETHYL)-2-SULFIDOTETRAHYDROFURO[3,4-D][1,3,2]DIOXAPHOSPHOL-4-YL]PYRIMIDINE-2,4(1H,3H)-DIONE'>UPT</scene>, <scene name='pdbligand=URI:URIDINE'>URI | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=06S:O-[(2R,3S,4R,5R)-5-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)-2-({[(S)-({(2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-HYDROXY-2-[(THIOPHOSPHONOOXY)METHYL]TETRAHYDROFURAN-3-YL}OXY)(SULFANYL)PHOSPHORYL]OXY}METHYL)-4-HYDROXYTETRAHYDROFURAN-3-YL]+DIHYDROGEN+(S)-PHOSPHOROTHIOATE'>06S</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=UPT:1-[(2R,3AR,4R,6R,6AR)-2-HYDROXY-6-(HYDROXYMETHYL)-2-SULFIDOTETRAHYDROFURO[3,4-D][1,3,2]DIOXAPHOSPHOL-4-YL]PYRIMIDINE-2,4(1H,3H)-DIONE'>UPT</scene>, <scene name='pdbligand=URI:URIDINE'>URI</scene></td></tr> |
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r07|4r07]], [[4r08|4r08]], [[4r0a|4r0a]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r07|4r07]], [[4r08|4r08]], [[4r0a|4r0a]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TLR8, UNQ249/PRO286 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r09 OCA], [http://pdbe.org/4r09 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r09 RCSB], [http://www.ebi.ac.uk/pdbsum/4r09 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r09 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r09 OCA], [http://pdbe.org/4r09 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r09 RCSB], [http://www.ebi.ac.uk/pdbsum/4r09 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r09 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Ohto, U]] | [[Category: Ohto, U]] | ||
[[Category: Shimizu, T]] | [[Category: Shimizu, T]] | ||
Revision as of 09:38, 24 April 2019
Crystal structure of human TLR8 in complex with ORN06S
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