4qmm

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==MST3 IN COMPLEX WITH AT-9283, 4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM==
==MST3 IN COMPLEX WITH AT-9283, 4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM==
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<StructureSection load='4qmm' size='340' side='right' caption='[[4qmm]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='4qmm' size='340' side='right'caption='[[4qmm]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qmm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QMM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QMM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qmm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QMM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QMM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=35R:1-CYCLOPROPYL-3-{3-[5-(MORPHOLIN-4-YLMETHYL)-1H-BENZIMIDAZOL-2-YL]-1H-PYRAZOL-4-YL}UREA'>35R</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=35R:1-CYCLOPROPYL-3-{3-[5-(MORPHOLIN-4-YLMETHYL)-1H-BENZIMIDAZOL-2-YL]-1H-PYRAZOL-4-YL}UREA'>35R</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qml|4qml]], [[4qmn|4qmn]], [[4qmo|4qmo]], [[4qmp|4qmp]], [[4qmq|4qmq]], [[4qmr|4qmr]], [[4qms|4qms]], [[4qmt|4qmt]], [[4qmu|4qmu]], [[4qmv|4qmv]], [[4qmw|4qmw]], [[4qmx|4qmx]], [[4qmy|4qmy]], [[4qmz|4qmz]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qml|4qml]], [[4qmn|4qmn]], [[4qmo|4qmo]], [[4qmp|4qmp]], [[4qmq|4qmq]], [[4qmr|4qmr]], [[4qms|4qms]], [[4qmt|4qmt]], [[4qmu|4qmu]], [[4qmv|4qmv]], [[4qmw|4qmw]], [[4qmx|4qmx]], [[4qmy|4qmy]], [[4qmz|4qmz]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MST3, STK24, STK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qmm OCA], [http://pdbe.org/4qmm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qmm RCSB], [http://www.ebi.ac.uk/pdbsum/4qmm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qmm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qmm OCA], [http://pdbe.org/4qmm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qmm RCSB], [http://www.ebi.ac.uk/pdbsum/4qmm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qmm ProSAT]</span></td></tr>
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</div>
</div>
<div class="pdbe-citations 4qmm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4qmm" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Olesen, S H]]
[[Category: Olesen, S H]]

Revision as of 09:42, 24 April 2019

MST3 IN COMPLEX WITH AT-9283, 4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM

PDB ID 4qmm

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