Casein kinase
From Proteopedia
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</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of casein kinase == | ||
| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *CK1 | ||
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| - | **[[5fqd]] - hCK1-α + DNA damage-binding protein + cereblon - human <br /> | ||
| - | **[[5fqd]] - hCK1-α + inhibitor <br /> | ||
| - | **[[2c47]] – hCK1-γ2 <br /> | ||
| - | **[[2chl]] - hCK1-γ3<br /> | ||
| - | **[[2cmw]] – hCK1-γ1 + inhibitor<br /> | ||
| - | **[[2izr]], [[2izs]], [[2izu]], [[2izt]], [[4g16]], [[4g17]], [[4hgl]], [[4hgs]], [[6gro]] - hCK1-γ3 + inhibitor<br /> | ||
| - | **[[3uys]], [[5ih4]] – hCK1-δ<br /> | ||
| - | **[[3uyt]], [[3uzp]], [[4hgt]], [[4hnf]], [[4kb8]], [[4kba]], [[4kbc]], [[4kbk]], [[5ih5]], [[5ih6]], [[4tn6]], [[5mqv]], [[6gzm]], [[6f26]], [[5okt]] – hCK1-δ + inhibitor<br /> | ||
| - | **[[4tw9]], [[4twc]] – hCK1-δ (mutant) + inhibitor<br /> | ||
| - | **[[1cki]] – rCK1-δ (mutant) – rat<br /> | ||
| - | **[[1ckj]] - rCK1-δ (mutant) + WO4<br /> | ||
| - | **[[4jjr]] - moCK1-δ - mouse<br /> | ||
| - | **[[5x17]] - moCK1-δ + ADP<br /> | ||
| - | **[[4hok]] - hCK1-ε <br /> | ||
| - | **[[4hni]], [[5w4w]] - hCK1-ε + inhibitor<br /> | ||
| - | **[[1csn]] – yCK1 + MgATP – fission yeast<br /> | ||
| - | **[[2csn]], [[1eh4]] – yCK1 catalytic domain + inhibitor | ||
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| - | *CK2A1 catalytic subunit | ||
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| - | **[[1pjk]], [[3at2]], [[3q04]], [[3qa0]], [[3war]], [[5t1h]] - hCK2A1 <br /> | ||
| - | **[[1na7]], [[3fwq]], [[3juh]], [[5cu6]], [[5cvg]], [[5zn0]], [[5zn1]], [[5zn2]], [[5zn3]], [[5zn4]], [[5zn5]] - hCK2A1 (mutant)<br /> | ||
| - | **[[3axw]], [[3r0t]], [[3u4u]] – hCK2A1 + inhibitor<br /> | ||
| - | **[[2r7i]] - rCK2A1 <br /> | ||
| - | **[[1lpu]], [[1lr4]], [[1jam]] - mCK2A1 <br /> | ||
| - | **[[6o6q]] - CK2A1 – ''Candida albicans''<br /> | ||
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| - | *CK2A1 catalytic subunit binary complex | ||
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| - | **[[3u87]] – hCK2A1 + ATP analog<br /> | ||
| - | **[[3q9w]], [[3q9x]], [[3bqc]], [[3c13]] – hCK2A1 + emodin<br /> | ||
| - | **[[3q9y]], [[3q9z]] – hCK2A1 + quinalizarin<br /> | ||
| - | **[[3u9c]] – hCK2A1 + resorufin<br /> | ||
| - | **[[2pvr]] - hCK2A1 + sulfate<br /> | ||
| - | **[[3nsz]], [[3wow]] - hCK2A1 + AMPPN<br /> | ||
| - | **[[3w8l]], [[5cvh]] - hCK2A1 (mutant) + inositol hexakisphosphate<br /> | ||
| - | **[[3e3b]], [[2zjw]], [[3h30]], [[3mb6]], [[3mb7]], [[3nga]], [[3rps]], [[3pe1]], [[3pe2]], [[3amy]], [[3at3]], [[3at4]], [[4anm]], [[4grb]], [[4gub]], [[3axw]], [[3r0t]], [[3u4u]], [[3owj]], [[3owk]], [[3owl]], [[3wik]], [[3wil]], [[5cqw]], [[5cqu]], [[4kwp]], [[4rll]], [[5m44]], [[5m4c]], [[5m4f]], [[5m4i]], [[5h8b]], [[5h8e]], [[5h8g]], [[5b0x]], [[4ub7]], [[4uba]], [[5omy]], [[5nqc]], [[5n9n]], [[5n9l]], [[5n1v]], [[5kwh]], [[5ku8]], [[6hme]], [[6hbn]], [[6f1w]], [[6a1c]], [[5owl]], [[5owh]] - hCK2A1 + inhibitor<br /> | ||
| - | **[[5m4u]], [[5m56]], [[5clp]], [[5cs6]], [[5csh]], [[5csp]], [[5csv]], [[5ct0]], [[5ctp]], [[5cu0]], [[5cu2]], [[5cu3]], [[5cu4]], [[5cvf]], [[5cx9]], [[6ehk]], [[6ehu]], [[6eii]], [[5oyf]], [[5ouu]], [[5oum]], [[5oul]], [[5oue]], [[5otz]], [[5oty]], [[5otr]], [[5otq]], [[5oto]], [[5otl]], [[5oti]], [[5oth]], [[5otd]], [[5ot6]], [[5ot5]], [[5osz]], [[5osl]], [[5os8]], [[5os7]], [[5ork]], [[5orj]], [[5orh]], [[5oqu]], [[5ooi]], [[5oni]], [[5n9k]], [[5mpj]], [[5mp8]], [[5mow]], [[5mov]], [[5mot]], [[5moh]], [[5moe]], [[5mod]], [[5mo8]], [[5mo7]], [[5mo6]], [[5mo5]], [[5mmr]], [[5mmf]], [[6gmd]], [[6gih]], [[5ots]], [[5otp]], [[5osu]], [[5osr]], [[5osp]] - hCK2A1 (mutant) + inhibitor<br /> | ||
| - | **[[4fbx]] - hCK2A1 + polypeptide inhibitor<br /> | ||
| - | **[[4ib5]] - hCK2A1 + hCK2 β polypeptide <br /> | ||
| - | **[[2pvh]], [[2pvj]], [[2pvk]], [[2pvl]], [[2pvm]], [[2pvn]], [[3be9]] - mCK2 (mutant) + inhibitor<br /> | ||
| - | **[[1f0q]], [[3pzh]] – mCK2A1 + emodin<br /> | ||
| - | **[[1zoe]], [[1zog]], [[1zoh]] – mCK2A1 + TBB derivative<br /> | ||
| - | **[[1j91]], [[4rlk]], [[5ts8]] - mCK2A1 + ATP competitive inhibitor - maize<br /> | ||
| - | **[[1lp4]], [[1daw]], [[1day]] - mCK2A1 + Mg-AMPPNP<br /> | ||
| - | **[[4dgm]] - mCK2A1 + apigenin<br /> | ||
| - | **[[4dgn]] - mCK2A1 + luteolin<br /> | ||
| - | **[[6qs5]] - mCK2A1 + tyrphostin<br /> | ||
| - | **[[1m2p]], [[1m2q]], [[1m2r]], [[1om1]], [[2oxd]], [[2oxx]], [[2oxy]], [[2qc6]], [[2pvh]], [[3fl5]], [[3kxg]], [[3kxh]], [[3kxm]], [[3kxn]], [[3pvg]], [[3pwd]] - mCK2A1 + inhibitor | ||
| - | **[[4fi1]], [[4mwh]] - yCK2A1 + ATP<br /> | ||
| - | **[[4jqe]] - yCK2A1 + AMPPN<br /> | ||
| - | **[[4jr7]], [[4lfi]] - yCK2A1 + GMPPNP<br /> | ||
| - | **[[5xvu]] - CK2A1 + ATP – ''Plasmodium falciparum''<br /> | ||
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| - | *CK2A2 catalytic subunit | ||
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| - | **[[5ywm]], [[5yf9]], [[5y9m]] - hCK2A2 <br /> | ||
| - | **[[3ofm]] - hCK2A2 (mutant)<br /> | ||
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| - | *CK2A2 catalytic subunit binary complex | ||
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| - | **[[3e3b]], [[6qy9]] - hCK2A2 + inhibitor<br /> | ||
| - | **[[5m4u]], [[5m56]], [[5ooi]], [[6hmb]], [[6hmc]], [[6hmd]], [[6hmq]] - hCK2A2 (mutant) + inhibitor<br /> | ||
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| - | *CK2 regulatory subunit | ||
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| - | **[[1qf8]], [[3eed]] – hCK2 β subunit | ||
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| - | **[[2r6m]] - rCK2 β subunit | ||
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| - | **[[1rqf]] - CK2 β subunit + cyclin-dependent kinase peptide – ''Xenopus laevis'' | ||
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| - | *CK2 catalytic + regulatory subunits | ||
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| - | **[[1jwh]], [[4md7]] - hCK2 α subunit + β subunit<br /> | ||
| - | **[[4dgl]], [[4md8]], [[4md9]] - hCK2 α subunit (mutant) + β subunit<br /> | ||
| - | **[[4nh1]] - hCK2 α subunit + β subunit (mutant)<br /> | ||
| - | **[[1ds5]] - mCK2 α subunit + β subunit peptide | ||
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| - | *Golgi casein kinase | ||
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| - | **[[4kqb]], [[4kqa]] - GCK – nematode<br /> | ||
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| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Eide EJ, Virshup DM. Casein kinase I: another cog in the circadian clockworks. Chronobiol Int. 2001 May;18(3):389-98. PMID:11475410
- ↑ Pinna LA, Meggio F. Protein kinase CK2 ("casein kinase-2") and its implication in cell division and proliferation. Prog Cell Cycle Res. 1997;3:77-97. PMID:9552408
- ↑ Hua Z, Huang X, Bregman H, Chakka N, DiMauro EF, Doherty EM, Goldstein J, Gunaydin H, Huang H, Mercede S, Newcomb J, Patel VF, Turci SM, Yan J, Wilson C, Martin MW. 2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1gamma) inhibitors. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5392-5. doi: 10.1016/j.bmcl.2012.07.046. , Epub 2012 Jul 20. PMID:22877629 doi:10.1016/j.bmcl.2012.07.046
