6qcc
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM Atomic Structure of Broad Bean Stain Virus (BBSV)== | |
| + | <StructureSection load='6qcc' size='340' side='right'caption='[[6qcc]], [[Resolution|resolution]] 3.22Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6qcc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Broad_bean_stain_virus Broad bean stain virus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=5npx 5npx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QCC FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qcc OCA], [http://pdbe.org/6qcc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qcc RCSB], [http://www.ebi.ac.uk/pdbsum/6qcc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qcc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The Broad bean stain virus (BBSV) is a member of the genus Comovirus infecting Fabaceae. The virus is transmitted through seed and by plant weevils causing severe and widespread disease worldwide. BBSV has a bipartite, positive-sense, single-stranded RNA genome encapsidated in icosahedral particles. We present here the cryo-electron microscopy reconstruction of the BBSV and an atomic model of the capsid proteins refined at 3.22A resolution. We identified residues involved in RNA/capsid interactions revealing a unique RNA genome organization. Inspection of the small coat protein C-terminal domain highlights a maturation cleavage between Leu567 and Leu568 and interactions of the C-terminal stretch with neighbouring small coat proteins within the capsid pentameric turrets. These interactions previously proposed to play a key role in the assembly of the Cowpea mosaic virus suggest a common capsid assembly mechanism throughout all comovirus species. | ||
| - | + | The cryo-electron microscopy structure of Broad Bean Stain Virus suggests a common capsid assembly mechanism among comoviruses.,Lecorre F, Lai-Kee-Him J, Blanc S, Zeddam JL, Trapani S, Bron P Virology. 2019 Apr;530:75-84. doi: 10.1016/j.virol.2019.02.009. Epub 2019 Feb 13. PMID:30782565<ref>PMID:30782565</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 6qcc" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Broad bean stain virus]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Blanc, S]] | [[Category: Blanc, S]] | ||
| - | [[Category: Lecorre, F]] | ||
[[Category: Bron, P]] | [[Category: Bron, P]] | ||
| - | [[Category: | + | [[Category: Him, J Lai Jee]] |
| - | [[Category: | + | [[Category: Lecorre, F]] |
[[Category: Trapani, S]] | [[Category: Trapani, S]] | ||
| + | [[Category: Zeddam, J L]] | ||
| + | [[Category: Comovirus capsid plant virus bbsv]] | ||
| + | [[Category: Virus]] | ||
Revision as of 08:38, 1 May 2019
Cryo-EM Atomic Structure of Broad Bean Stain Virus (BBSV)
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