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6d4t
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 45 (VCC117054)== | |
| - | + | <StructureSection load='6d4t' size='340' side='right'caption='[[6d4t]], [[Resolution|resolution]] 1.54Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6d4t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D4T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FWS:(2S)-N-(2H-1,3-benzodioxol-5-yl)-4-[(isoquinolin-5-yl)sulfonyl]-2-methylpiperazine-1-carboxamide'>FWS</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d4t OCA], [http://pdbe.org/6d4t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d4t RCSB], [http://www.ebi.ac.uk/pdbsum/6d4t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d4t ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/G7CNL4_MYCT3 G7CNL4_MYCT3]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ascher, D B]] | ||
| + | [[Category: Blundell, T L]] | ||
[[Category: Pacitto, A]] | [[Category: Pacitto, A]] | ||
| + | [[Category: Complex]] | ||
| + | [[Category: Fragment]] | ||
| + | [[Category: Impdh]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | ||
Revision as of 08:43, 1 May 2019
M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 45 (VCC117054)
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