6jve
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the ternary complex of peptidoglycan recognition protein, PGRP-S with tartaric acid and hexanoic acid at 2.28 A resolution== | |
| - | + | <StructureSection load='6jve' size='340' side='right'caption='[[6jve]], [[Resolution|resolution]] 2.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6jve]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JVE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6NA:HEXANOIC+ACID'>6NA</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jve OCA], [http://pdbe.org/6jve PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jve RCSB], [http://www.ebi.ac.uk/pdbsum/6jve PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jve ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Camelus dromedarius]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Sharma, P]] | ||
| + | [[Category: Sharma, S]] | ||
| + | [[Category: Singh, T P]] | ||
[[Category: Viswanathan, V]] | [[Category: Viswanathan, V]] | ||
| - | [[Category: | + | [[Category: Immune system]] |
| - | + | ||
| - | + | ||
Revision as of 08:53, 1 May 2019
Crystal Structure of the ternary complex of peptidoglycan recognition protein, PGRP-S with tartaric acid and hexanoic acid at 2.28 A resolution
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