6q83
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the biportin Pdr6 in complex with UBC9== | |
| - | + | <StructureSection load='6q83' size='340' side='right'caption='[[6q83]], [[Resolution|resolution]] 4.53Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6q83]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q83 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q83 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q83 OCA], [http://pdbe.org/6q83 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q83 RCSB], [http://www.ebi.ac.uk/pdbsum/6q83 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q83 ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/KA122_YEAST KA122_YEAST]] Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm. Required for the nuclear import of the complex composed the large subunit (TOA1) and the small subunit (TOA2) of the general transcription factor IIA (TFIIA). Required for the nuclear import of the RNR2-RNR4 heterodimer, also called beta-beta' subunit, which corresponds to the small subunit of the ribonucleotide reductase (RNR). May play a role in regulation of pleiotropic drug resistance.<ref>PMID:10525531</ref> <ref>PMID:16432237</ref> <ref>PMID:1882553</ref> <ref>PMID:18838542</ref> [[http://www.uniprot.org/uniprot/UBC9_YEAST UBC9_YEAST]] E2 ubiquitin-like--protein ligase mediating SUMO/Smt3 attachment to septins and PCNA. Seems to be involved in degradation of S- (CLB5) and M-phase cyclins (CLB2).<ref>PMID:9341106</ref> <ref>PMID:11572779</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Aksu, M]] | ||
| + | [[Category: Gorlich, D]] | ||
| + | [[Category: Trakhanov, S]] | ||
| + | [[Category: Vera-Rodriguez, A]] | ||
| + | [[Category: Biportin]] | ||
| + | [[Category: Importin-beta family]] | ||
| + | [[Category: Nuclear import]] | ||
| + | [[Category: Protein transport]] | ||
| + | [[Category: Sumoylation]] | ||
Revision as of 08:57, 1 May 2019
Crystal structure of the biportin Pdr6 in complex with UBC9
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