6r65

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m (Protected "6r65" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 6r65 is ON HOLD
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==Crystal Structure of human TMEM16K / Anoctamin 10 (Form 2)==
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<StructureSection load='6r65' size='340' side='right'caption='[[6r65]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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Authors: Bushell, S.R., Pike, A.C.W., Chu, A., Tessitore, A., Rotty, B., Mukhopadhyay, S., Kupinska, K., Shrestha, L., Borkowska, O., Chalk, R., Burgess-Brown, N.A., Love, J., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Carpenter, E.P., Structural Genomics Consortium (SGC)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6r65]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R65 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R65 FirstGlance]. <br>
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Description: Crystal Structure of human TMEM16K / Anoctamin 10 (Form 2)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5oc9|5oc9]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r65 OCA], [http://pdbe.org/6r65 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r65 RCSB], [http://www.ebi.ac.uk/pdbsum/6r65 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r65 ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Adult-onset autosomal recessive cerebellar ataxia. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.<ref>PMID:20056604</ref> <ref>PMID:22946059</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Borkowska, O]]
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[[Category: Bountra, C]]
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[[Category: Burgess-Brown, N A]]
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[[Category: Bushell, S R]]
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[[Category: Carpenter, E P]]
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[[Category: Chalk, R]]
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[[Category: Chu, A]]
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[[Category: Edwards, A M]]
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[[Category: Kupinska, K]]
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[[Category: Love, J]]
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[[Category: Mukhopadhyay, S]]
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[[Category: Pike, A C.W]]
[[Category: Rotty, B]]
[[Category: Rotty, B]]
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[[Category: Pike, A.C.W]]
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[[Category: Structural genomic]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Chalk, R]]
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[[Category: Borkowska, O]]
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[[Category: Shrestha, L]]
[[Category: Shrestha, L]]
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[[Category: Love, J]]
 
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[[Category: Burgess-Brown, N.A]]
 
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[[Category: Chu, A]]
 
[[Category: Tessitore, A]]
[[Category: Tessitore, A]]
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[[Category: Edwards, A.M]]
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[[Category: Calcium activation]]
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[[Category: Mukhopadhyay, S]]
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[[Category: Lipid transport]]
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[[Category: Structural Genomics Consortium (Sgc)]]
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[[Category: Membrane protein]]
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[[Category: Carpenter, E.P]]
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[[Category: Sgc]]
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[[Category: Bountra, C]]
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[[Category: Transport protein]]
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[[Category: Bushell, S.R]]
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[[Category: Kupinska, K]]
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Revision as of 08:58, 1 May 2019

Crystal Structure of human TMEM16K / Anoctamin 10 (Form 2)

PDB ID 6r65

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