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4rl2

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==Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins==
==Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins==
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<StructureSection load='4rl2' size='340' side='right' caption='[[4rl2]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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<StructureSection load='4rl2' size='340' side='right'caption='[[4rl2]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rl2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RL2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rl2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RL2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RL2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3S3:(1R)-2-({(R)-CARBOXY[(2R,5S)-4-CARBOXY-5-METHYL-5,6-DIHYDRO-2H-1,3-THIAZIN-2-YL]METHYL}AMINO)-2-OXO-1-PHENYLETHANAMINIUM'>3S3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3S3:(1R)-2-({(R)-CARBOXY[(2R,5S)-4-CARBOXY-5-METHYL-5,6-DIHYDRO-2H-1,3-THIAZIN-2-YL]METHYL}AMINO)-2-OXO-1-PHENYLETHANAMINIUM'>3S3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaNDM-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rl2 OCA], [http://pdbe.org/4rl2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rl2 RCSB], [http://www.ebi.ac.uk/pdbsum/4rl2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rl2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rl2 OCA], [http://pdbe.org/4rl2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rl2 RCSB], [http://www.ebi.ac.uk/pdbsum/4rl2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rl2 ProSAT]</span></td></tr>
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==See Also==
==See Also==
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*[[Beta-lactamase|Beta-lactamase]]
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
[[Category: Ding, J]]
[[Category: Ding, J]]
[[Category: Feng, H]]
[[Category: Feng, H]]

Revision as of 10:33, 1 May 2019

Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins

PDB ID 4rl2

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