6dbp
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==RNA-recognition motif 1 of human MSI2== | |
| - | + | <StructureSection load='6dbp' size='340' side='right'caption='[[6dbp]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dbp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DBP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DBP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dbp OCA], [http://pdbe.org/6dbp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dbp RCSB], [http://www.ebi.ac.uk/pdbsum/6dbp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dbp ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/MSI2H_HUMAN MSI2H_HUMAN]] Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).<ref>PMID:12649177</ref> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MSI2H_HUMAN MSI2H_HUMAN]] RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity). | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Goldgur, Y]] | ||
| + | [[Category: Kharas, M G]] | ||
[[Category: Minuesa, G]] | [[Category: Minuesa, G]] | ||
| - | [[Category: | + | [[Category: Musashi2 rna recognition motif]] |
| - | [[Category: | + | [[Category: Rna binding protein]] |
Revision as of 11:14, 10 May 2019
RNA-recognition motif 1 of human MSI2
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