This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5izb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Murin CXCL13 solution structure featuring a folded N-terminal domain== | ==Murin CXCL13 solution structure featuring a folded N-terminal domain== | ||
| - | <StructureSection load='5izb' size='340' side='right' caption='[[5izb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | + | <StructureSection load='5izb' size='340' side='right'caption='[[5izb]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5izb]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IZB FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5izb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IZB FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5izb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5izb OCA], [http://pdbe.org/5izb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5izb RCSB], [http://www.ebi.ac.uk/pdbsum/5izb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5izb ProSAT]</span></td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cxcl13, Blc, Scyb13 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5izb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5izb OCA], [http://pdbe.org/5izb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5izb RCSB], [http://www.ebi.ac.uk/pdbsum/5izb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5izb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/CXL13_MOUSE CXL13_MOUSE]] Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs. | [[http://www.uniprot.org/uniprot/CXL13_MOUSE CXL13_MOUSE]] Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[C-X-C motif chemokine|C-X-C motif chemokine]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lk3 transgenic mice]] | ||
[[Category: Lortat-Jacob, H]] | [[Category: Lortat-Jacob, H]] | ||
[[Category: Monneau, Y R]] | [[Category: Monneau, Y R]] | ||
[[Category: Chemokine structure n-terminal domain conformational exchange]] | [[Category: Chemokine structure n-terminal domain conformational exchange]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
Revision as of 13:03, 10 May 2019
Murin CXCL13 solution structure featuring a folded N-terminal domain
| |||||||||||
