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4twc

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==2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e==
==2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e==
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<StructureSection load='4twc' size='340' side='right' caption='[[4twc]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4twc' size='340' side='right'caption='[[4twc]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4twc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TWC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4twc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TWC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=37J:2-{[2-(TRIFLUOROMETHOXY)BENZOYL]AMINO}-N-[6-(TRIFLUOROMETHYL)-1H-BENZIMIDAZOL-2-YL]-1,3-THIAZOLE-4-CARBOXAMIDE'>37J</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=37J:2-{[2-(TRIFLUOROMETHOXY)BENZOYL]AMINO}-N-[6-(TRIFLUOROMETHYL)-1H-BENZIMIDAZOL-2-YL]-1,3-THIAZOLE-4-CARBOXAMIDE'>37J</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSNK1D, HCKID ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4twc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4twc OCA], [http://pdbe.org/4twc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4twc RCSB], [http://www.ebi.ac.uk/pdbsum/4twc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4twc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4twc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4twc OCA], [http://pdbe.org/4twc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4twc RCSB], [http://www.ebi.ac.uk/pdbsum/4twc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4twc ProSAT]</span></td></tr>
</table>
</table>
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==See Also==
==See Also==
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*[[Casein kinase|Casein kinase]]
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*[[Casein kinase 3D structures|Casein kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Bischof, J]]
[[Category: Bischof, J]]
[[Category: Grothey, A]]
[[Category: Grothey, A]]

Revision as of 14:15, 10 May 2019

2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4- carboxamide derivatives as potent inhibitors of CK1d/e

PDB ID 4twc

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