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4u6o
From Proteopedia
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==STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2== | ==STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2== | ||
| - | <StructureSection load='4u6o' size='340' side='right' caption='[[4u6o]], [[Resolution|resolution]] 1.30Å' scene=''> | + | <StructureSection load='4u6o' size='340' side='right'caption='[[4u6o]], [[Resolution|resolution]] 1.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4u6o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U6O FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4u6o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/I34a1 I34a1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U6O FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u6o OCA], [http://pdbe.org/4u6o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u6o RCSB], [http://www.ebi.ac.uk/pdbsum/4u6o PDBsum]</span></td></tr> | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PB2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=211044 I34A1])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u6o OCA], [http://pdbe.org/4u6o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u6o RCSB], [http://www.ebi.ac.uk/pdbsum/4u6o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u6o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/PB2_I34A1 PB2_I34A1]] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity). | [[http://www.uniprot.org/uniprot/PB2_I34A1 PB2_I34A1]] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity). | ||
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| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: I34a1]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Fukushima, K]] | [[Category: Fukushima, K]] | ||
[[Category: Takimoto-Kamimura, M]] | [[Category: Takimoto-Kamimura, M]] | ||
Revision as of 14:33, 10 May 2019
STRUCTURE OF THE CAP-BINDING DOMAIN OF INFLUENZA VIRUS POLYMERASE SUBUNIT PB2
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