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4try
From Proteopedia
(Difference between revisions)
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==Structure of BACE1 complex with a HEA-type inhibitor== | ==Structure of BACE1 complex with a HEA-type inhibitor== | ||
| - | <StructureSection load='4try' size='340' side='right' caption='[[4try]], [[Resolution|resolution]] 2.75Å' scene=''> | + | <StructureSection load='4try' size='340' side='right'caption='[[4try]], [[Resolution|resolution]] 2.75Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4try]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TRY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TRY FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4try]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TRY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TRY FirstGlance]. <br> |
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=36D:N-[(2R,3S)-3-AMINO-2-HYDROXY-4-(THIOPHEN-2-YL)BUTANOYL]-L-NORVALINE'>36D</scene>, <scene name='pdbligand=TIH:BETA(2-THIENYL)ALANINE'>TIH</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=36D:N-[(2R,3S)-3-AMINO-2-HYDROXY-4-(THIOPHEN-2-YL)BUTANOYL]-L-NORVALINE'>36D</scene>, <scene name='pdbligand=TIH:BETA(2-THIENYL)ALANINE'>TIH</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4trw|4trw]], [[4trz|4trz]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4trw|4trw]], [[4trz|4trz]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE1, BACE, KIAA1149 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4try FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4try OCA], [http://pdbe.org/4try PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4try RCSB], [http://www.ebi.ac.uk/pdbsum/4try PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4try ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4try FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4try OCA], [http://pdbe.org/4try PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4try RCSB], [http://www.ebi.ac.uk/pdbsum/4try PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4try ProSAT]</span></td></tr> | ||
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==See Also== | ==See Also== | ||
| - | *[[Beta secretase|Beta secretase]] | + | *[[Beta secretase 3D structures|Beta secretase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Akaji, K]] | [[Category: Akaji, K]] | ||
Revision as of 14:45, 10 May 2019
Structure of BACE1 complex with a HEA-type inhibitor
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