Cholesterol esterase
From Proteopedia
(Difference between revisions)
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ChoE <scene name='52/525136/Cv/9'>ligand-binding tunnel is ca. 30 A long</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}). ChoE has the <scene name='52/525136/Cv/10'>polar catalytic triad Ser-His-Glu</scene> at the opening and <scene name='52/525136/Cv/11'>hydrophobic residues lining the bottom cup</scene>.<ref>PMID:12499539</ref> | ChoE <scene name='52/525136/Cv/9'>ligand-binding tunnel is ca. 30 A long</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}). ChoE has the <scene name='52/525136/Cv/10'>polar catalytic triad Ser-His-Glu</scene> at the opening and <scene name='52/525136/Cv/11'>hydrophobic residues lining the bottom cup</scene>.<ref>PMID:12499539</ref> | ||
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| + | ==3D structures of cholesterol esterase== | ||
| + | [[Cholesterol esterase 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
==3D structures of cholesterol esterase== | ==3D structures of cholesterol esterase== | ||
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*Cholesterol esterase | *Cholesterol esterase | ||
| + | **[[1jmy]] – hChoE catalytic domain- human<br /> | ||
| + | **[[1f6w]], [[6h0t]] – hChoE catalytic domain (mutant) <br /> | ||
**[[1akn]] – bChoE – bovine<br /> | **[[1akn]] – bChoE – bovine<br /> | ||
**[[2bce]] – bChoE (mutant)<br /> | **[[2bce]] – bChoE (mutant)<br /> | ||
| - | **[[1jmy]] – hChoE - human<br /> | ||
| - | **[[1f6w]] – hChoE catalytic domain (mutant) <br /> | ||
**[[4be9]], [[4be4]] – OpChoE – ''Ophiostoma piceae''<br /> | **[[4be9]], [[4be4]] – OpChoE – ''Ophiostoma piceae''<br /> | ||
**[[4upd]] – OpChoE (mutant) <br /> | **[[4upd]] – OpChoE (mutant) <br /> | ||
| - | *Cholesterol esterase complex | + | *Cholesterol esterase complex |
| + | **[[6h0v]] – hChoE (mutant) + tabun<br /> | ||
| + | **[[6h18]] – hChoE (mutant) + sarin<br /> | ||
| + | **[[6h19]] – hChoE (mutant) + paraoxon<br /> | ||
| + | **[[6h1a]] – hChoE (mutant) + VX<br /> | ||
| + | **[[1aql]] – bChoE + taurocholate<br /> | ||
**[[1cle]] – CcChoE + cholesteryl linoleate – ''Candida cylindracea''<br /> | **[[1cle]] – CcChoE + cholesteryl linoleate – ''Candida cylindracea''<br /> | ||
**[[1llf]] – CcChoE + tricosanoic acid<br /> | **[[1llf]] – CcChoE + tricosanoic acid<br /> | ||
| - | + | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:16, 12 May 2019
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3D structures of cholesterol esterase
Updated on 12-May-2019
References
- ↑ Moore SA, Kingston RL, Loomes KM, Hernell O, Blackberg L, Baker HM, Baker EN. The structure of truncated recombinant human bile salt-stimulated lipase reveals bile salt-independent conformational flexibility at the active-site loop and provides insights into heparin binding. J Mol Biol. 2001 Sep 21;312(3):511-23. PMID:11563913 doi:10.1006/jmbi.2001.4979
- ↑ Pletnev V, Addlagatta A, Wawrzak Z, Duax W. Three-dimensional structure of homodimeric cholesterol esterase-ligand complex at 1.4 A resolution. Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):50-6. Epub 2002 Dec, 19. PMID:12499539
