Choline kinase
From Proteopedia
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The choline binds to CK in a <scene name='59/593958/Cv/5'>deep hydrophobic groove</scene> (PDB code [[2ckq]]; {{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}) and the <scene name='59/593958/Cv/6'>ADP binds in a cleft</scene> (PDB code [[2ckp]]). <ref>PMID:17007874</ref> | The choline binds to CK in a <scene name='59/593958/Cv/5'>deep hydrophobic groove</scene> (PDB code [[2ckq]]; {{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}) and the <scene name='59/593958/Cv/6'>ADP binds in a cleft</scene> (PDB code [[2ckp]]). <ref>PMID:17007874</ref> | ||
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| + | ==3D structures of choline kinase== | ||
| + | [[Choline kinase 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
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**[[2ckp]] – hCK α2 + ADP<br /> | **[[2ckp]] – hCK α2 + ADP<br /> | ||
**[[2ckq]] – hCK α2 + phosphocholine<br /> | **[[2ckq]] – hCK α2 + phosphocholine<br /> | ||
| - | **[[3zm9]], [[4da5]], [[4br3]], [[5afv]], [[5eqe]], [[5eqp]], [[5eqy]], [[5ftg]], [[5fut]] – hCK α + inhibitor<br /> | + | **[[3zm9]], [[4da5]], [[4br3]], [[5afv]], [[5eqe]], [[5eqp]], [[5eqy]], [[5ftg]], [[5fut]], [[5w6o]] – hCK α + inhibitor<br /> |
**[[3f2r]] – hCK α + hemicholinium-3<br /> | **[[3f2r]] – hCK α + hemicholinium-3<br /> | ||
**[[3g15]] – hCK α + hemicholinium-3 + ADP<br /> | **[[3g15]] – hCK α + hemicholinium-3 + ADP<br /> | ||
Revision as of 10:28, 12 May 2019
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3D structures of choline kinase
Updated on 12-May-2019
References
- ↑ Malito E, Sekulic N, Too WC, Konrad M, Lavie A. Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine. J Mol Biol. 2006 Nov 24;364(2):136-51. Epub 2006 Sep 3. PMID:17007874 doi:10.1016/j.jmb.2006.08.084
