Complement C5
From Proteopedia
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Mutations in CC5 cause a deficiency leading to severe recurrent infections and are linked to liver fibrosis, Leiner's disease and rheumatoid arthritis. | Mutations in CC5 cause a deficiency leading to severe recurrent infections and are linked to liver fibrosis, Leiner's disease and rheumatoid arthritis. | ||
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| + | == 3D Structures of complement C5 == | ||
| + | [[Complement C5 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
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**[[5hcd]] – hCC5 + complement inhibitor + RACI2<BR /> | **[[5hcd]] – hCC5 + complement inhibitor + RACI2<BR /> | ||
**[[5hce]] – hCC5 + complement inhibitor + RACI1<BR /> | **[[5hce]] – hCC5 + complement inhibitor + RACI1<BR /> | ||
| + | **[[6h04]] – hCC5 + hCC9 + hCC8 a+b+g chains + hCC7 – Cryo EM<BR /> | ||
*C345C | *C345C | ||
Revision as of 06:37, 15 May 2019
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3D Structures of complement C5
Updated on 15-May-2019
References
- ↑ Fredslund F, Laursen NS, Roversi P, Jenner L, Oliveira CL, Pedersen JS, Nunn MA, Lea SM, Discipio R, Sottrup-Jensen L, Andersen GR. Structure of and influence of a tick complement inhibitor on human complement component 5. Nat Immunol. 2008 Jul;9(7):753-60. Epub 2008 Jun 8. PMID:18536718 doi:10.1038/ni.1625
