Indole-3-glycerol phosphate synthase

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== Structural highlights ==
== Structural highlights ==
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The <scene name='57/572309/Cv/5'>active site of IGPS containing the reaction product IGP</scene><ref>PMID:12054868</ref>. Water molecules shown as red spheres.
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The <scene name='57/572309/Cv/6'>active site of IGPS containing the reaction product IGP</scene><ref>PMID:12054868</ref>. Water molecules shown as red spheres.
</StructureSection>
</StructureSection>

Revision as of 13:05, 19 May 2019

Structure of IGPS complex with IGP (PDB entry 1a53)

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3D structures of IGPS

Updated on 19-May-2019

References

  1. Creighton TE, Yanofsky C. Indole-3-glycerol phosphate synthetase of Escherichia coli, an enzyme of the tryptophan operon. J Biol Chem. 1966 Oct 25;241(20):4616-24. PMID:5332729
  2. Hennig M, Darimont BD, Jansonius JN, Kirschner K. The catalytic mechanism of indole-3-glycerol phosphate synthase: crystal structures of complexes of the enzyme from Sulfolobus solfataricus with substrate analogue, substrate, and product. J Mol Biol. 2002 Jun 7;319(3):757-66. PMID:12054868 doi:http://dx.doi.org/10.1016/S0022-2836(02)00378-9

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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