4ubt
From Proteopedia
(Difference between revisions)
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==Structure of the C93S variant of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis in complex with a steroid and CoA.== | ==Structure of the C93S variant of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis in complex with a steroid and CoA.== | ||
| - | <StructureSection load='4ubt' size='340' side='right' caption='[[4ubt]], [[Resolution|resolution]] 1.70Å' scene=''> | + | <StructureSection load='4ubt' size='340' side='right'caption='[[4ubt]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4ubt]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UBT FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4ubt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UBT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UBT FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3G6:(2S)-2-[(8S,9S,10R,13S,14S,17R)-10,13-DIMETHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL]PROPANOIC+ACID+(NON-PREFERRED+NAME)'>3G6</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3G6:(2S)-2-[(8S,9S,10R,13S,14S,17R)-10,13-DIMETHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL]PROPANOIC+ACID+(NON-PREFERRED+NAME)'>3G6</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fadA5, Rv3546, P425_03688, RVBD_3546 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetyl-CoA_C-acyltransferase Acetyl-CoA C-acyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.16 2.3.1.16] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetyl-CoA_C-acyltransferase Acetyl-CoA C-acyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.16 2.3.1.16] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ubt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ubt OCA], [http://pdbe.org/4ubt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ubt RCSB], [http://www.ebi.ac.uk/pdbsum/4ubt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ubt ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ubt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ubt OCA], [http://pdbe.org/4ubt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ubt RCSB], [http://www.ebi.ac.uk/pdbsum/4ubt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ubt ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 4ubt" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 4ubt" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Thiolase|Thiolase]] | ||
| + | *[[User:Karsten Theis/FadA5 thiolase|User:Karsten Theis/FadA5 thiolase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Acetyl-CoA C-acyltransferase]] | [[Category: Acetyl-CoA C-acyltransferase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Myctu]] | ||
[[Category: Kisker, C]] | [[Category: Kisker, C]] | ||
[[Category: Schaefer, C M]] | [[Category: Schaefer, C M]] | ||
Revision as of 09:23, 21 May 2019
Structure of the C93S variant of the 3-ketoacyl-CoA thiolase FadA5 from M. tuberculosis in complex with a steroid and CoA.
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